Protein Alignment Cyp311a1 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 111/498 - (22%)
• Similarity: 217/498 - (43%)
• Gaps: 70/498 - (14%)

  Fly     6 LLLITLTIWILV--RKWTLLRLGSSLPGPWAFPLLGNAQMV----GKLRPEYIFLVFTELRDRFG 64
            :||::..|:||.  |:...||....|.||.....:||.:.:    .||..:.....|.||..::|
 Worm    11 ILLVSFIIYILFARREQFKLREKIGLTGPEPHWFMGNLKQIVDRKEKLGYDDSNKWFNELHKQYG 75

  Fly    65 ATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQ--LEPLIGNG------LLISHGAHWTR 121
            .|:.:..|.|:.:.|.:.|:.::..    ::....|..  :.|:..:.      |..::...|..
 Worm    76 ETFGIYFGAQMNIVLSNEEDIKEVF----IKNFSNFSDRIVPPIFDSNQLNQSLLQNTYATGWKH 136

  Fly   122 QRRLLTPAFQPQLLRSFAPAIGGHVERLVG--RLGATRGAFLEVTEPLFACLLDAI------VDT 178
            .|..:.|.|....:::....|...|:..:.  |..|:.|...::.|......||.|      :|:
 Worm   137 TRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREKASSGQKWDIYEDFQGLTLDVIGKCAFAIDS 201

  Fly   179 SMGAQLDTQSVDHSPIIQAFHLS------------SKLLFKRMINPLLSSDW--IFQRTQLWRDL 229
            :  .|.|...|        |:::            ||::....|.|.|:..|  :::.|.|   .
 Worm   202 N--CQRDRNDV--------FYVNARKFIANIDIRHSKVIAASFILPELAPLWRALYKYTPL---A 253

  Fly   230 DEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLD--TLLLAKFEGQS--LSRREIRDEINTF 290
            |.::.::.. :.:|.|:|.         .|...:.:|  .|||.:.:.:|  ::::|:.:....|
 Worm   254 DAEIPLVEG-LSNVYERRR---------GGEGSDSVDLLKLLLNREDDKSKPMTKQEVIENCFAF 308

  Fly   291 VFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRLY- 354
            :.||.:||:.||::..|.|:|:|..|.:|.:|:.:...:.....|:::.:.||:.:.||.||.|
 Worm   309 LLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGGLTYDSIHNMKYLDYVYKETLRCYP 373

  Fly   355 TIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFS 419
            .::....|:......|.|:.|..|..:....:.:..:.|.:..|..|.|||:  |:......:..
 Worm   374 PVIHFINRRCLADITIRGQFYPKGSVVTCLPHTVHLNPENWDSPEEFHPERF--ENWEEKSSSLK 436

  Fly   420 YIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPL 462
            :|||..||..|:|.|::.:..|....:|:..|:::....:|.|
 Worm   437 WIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFKGEADL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	93/434 (21%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	93/436 (21%)