Protein Alignment Cyp311a1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 145/509 - (28%)
• Similarity: 224/509 - (44%)
• Gaps: 65/509 - (12%)

  Fly     1 MALWPLLLITLTIWILVRKWT---LLRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLVFTELRDR 62
            |..|.||:|:|.:..|....:   ..:||  :|||...|.||.            .|.:.:....
  Rat     9 METWLLLVISLVLLYLYGTHSHGIFKKLG--IPGPKPLPFLGT------------ILAYRKGFWE 59

  Fly    63 FGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKA-------DTFMQLEPLIGNGLL-----ISH 115
            |......:.| :|| .|:...:...|:.||.:.|.       .||.........|:|     ||.
  Rat    60 FDKYCHKKYG-KLW-GLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISE 122

  Fly   116 GAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVG--RLGATRGAFLEVTEPLFACLLDAIVDT 178
            ...|.|.|.||:|.|....|:...|.|..:.:.||.  |.|:..|....:.:...|..:|.|..|
  Rat   123 DEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITAT 187

  Fly   179 SMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQ-RTQLWRDLD------EQLQVI 236
            |.|..:|:.:....|.::..   .|||...:.:||..|..:|. .|.|:..|:      :.:...
  Rat   188 SFGVNVDSLNNPQDPFVEKI---KKLLKFDIFDPLFLSVTLFPFLTPLFEALNVSMFPRDVIDFF 249

  Fly   237 HSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLL--------AKFEGQSLSRREIRDEINTFVFA 293
            .:.:|.:.|.|.||         :....:|.|.|        .|...::||..||..:...|:||
  Rat   250 KTSVERMKENRMKE---------KEKQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFIFA 305

  Fly   294 GVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDET--TDLDALNGLPYLEALIKEVLRLYTI 356
            |.:||::|:|||||.||..|:.|.:|:.|: |.||...  ...|.|..:.||:.::.|.||||.|
  Rat   306 GYETTSSALSFVLYLLAIHPDIQKKLQDEI-DAALPNKAHATYDTLLQMEYLDMVVNETLRLYPI 369

  Fly   357 VPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYI 421
            .....|......||.|.....|..:.|..:.|..|..|:|:|..|:|||:..::.....| :.|:
  Rat   370 AGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINP-YMYL 433

  Fly   422 PFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-QAPLRLEAQMVLKAQQ 474
            ||..||..|||.|::|:.||:...|:::.|..:...| |.||:|..|.:|:.::
  Rat   434 PFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPLKLSKQGLLQPEK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	128/443 (29%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	128/437 (29%)