Protein Alignment Cyp311a1 and CYP26A1

DIOPT Version :9

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 125/507 - (24%)
• Similarity: 217/507 - (42%)
• Gaps: 89/507 - (17%)

  Fly     5 PLLLITLTIWILVRKWTLLRLGSS--------LPGPWAFPLLGNA-QMVGKLRPEYIFLVFTEL- 59
            ||||....|    :.|.|..:...        .||...||..|.. |||.:.|.      |.::
Human    17 PLLLFLAAI----KLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRK------FLQMK 71

  Fly    60 RDRFGATYRLRLGPQLWVFLHSAEETRQAL---------HDPTLRKADTFMQLEPLIGNGLLIS- 114
            |.::|..|:..|..:..|.:..|:..|:.|         |.|.        .:..::|:|.|.:
Human    72 RRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPA--------SVRTILGSGCLSNL 128

  Fly   115 HGAHWTRQRRLLTPAFQPQLLRSFAPAI----GGHVERLV--GRLGATRGAFLEVTEPLFACLLD 173
            |.:...::::::..||..:.|..:.|.|    |..:|:.:  |..|..  .:.||...:|...:.
Human   129 HDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLL--VYPEVKRLMFRIAMR 191

  Fly   174 AIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHS 238
            .::...  .||.........:::||...::.||...|:...|.        |:|.:..: .:||:
Human   192 ILLGCE--PQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSG--------LYRGMKAR-NLIHA 245

  Fly   239 QMESVIEKRAKEL-LDMGEPAGRAHNLLDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAA 301
            ::|..|  |||.. |...|......:.|..|:...:| |:.|..:.::......:|.|.:||.:|
Human   246 RIEQNI--RAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASA 308

  Fly   302 MSFVLYALAKFPETQTRLRKELQDVAL------DETTDLDALNGLPYLEALIKEVLRLYTIVPTT 360
            .:.::..|..:|....::|:||:...|      |...|::.|..|.|:..:|||.|||...||..
Human   309 ATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGG 373

  Fly   361 GRQTTQSTEIGGRTYCAGVTLWINMYGL--AHD-KEYYPDPYAFKPERWL---PEDGAVAPPAFS 419
            .|...::.|:.|.....|   |..:|.:  .|| .|.:.:...|.|:|::   |||.:    .||
Human   374 FRVALKTFELNGYQIPKG---WNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDAS----RFS 431

  Fly   420 YIPFSGGPHVCIGRRYSLLLMKLLTARLVR--EFQ-------MELSPEQAPL 462
            :|||.||...|:|:.::.:|:|:.|..|.|  ::|       |:.||...|:
Human   432 FIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	118/474 (25%)
CYP26A1	NP_000774.2	p450	14..492	CDD:299894	125/507 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910