Protein Alignment Cyp311a1 and CYP19A1

DIOPT Version :9

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_000094.2
• Gene: CYP19A1 / 1588
• HGNCID: 2594
• Length: 503
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 114/542 - (21%)
• Similarity: 202/542 - (37%)
• Gaps: 161/542 - (29%)

  Fly     2 ALWPLLLITLTIWILVRKWTLLRLGSSLPGP----WAFPLLGNAQ-------------------- 42
            |..|:||:| .:::||  |. ....||:|||    ...||:.:.:
Human    24 ATMPVLLLT-GLFLLV--WN-YEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEF 84

  Fly    43 -----------MVGKLRPEYIFLVFTELRDRFGATYRLRL------------GPQLWVFLHSAEE 84
                       ::.|....:..:.......|||:...|:.            .|:||      :.
Human    85 MRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELW------KT 143

  Fly    85 TRQALHDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERL 149
            ||     |...||        |.|.||:           |::|..         |.::..|::||
Human   144 TR-----PFFMKA--------LSGPGLV-----------RMVTVC---------AESLKTHLDRL 175

  Fly   150 ---------VGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPII---------- 195
                     |..|...|...|:.:..||..:                .:|.|.|:
Human   176 EEVTNESGYVDVLTLLRRVMLDTSNTLFLRI----------------PLDESAIVVKIQGYFDAW 224

  Fly   196 QAFHLSSKLLFKRMINPLLSSDWIFQR-TQLWRDLDEQLQVIHSQMESVI--EKRAKELLDMGEP 257
            ||..:...:.||        ..|:::: .:..:||.:.::|:.::....|  |::.:|.:|..
Human   225 QALLIKPDIFFK--------ISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFA-- 279

  Fly   258 AGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKE 322
                    ..|:||:..| .|:|..:...|...:.|..||.:.::.|:|:.:||.|..:..:.||
Human   280 --------TELILAEKRG-DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKE 335

  Fly   323 LQDVALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYG 387
            :|.|..:....:|.:..|..:|..|.|.:|...:|....|:..:...|.|.....|..:.:|: |
Human   336 IQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNI-G 399

  Fly   388 LAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQ 452
            ..|..|::|     ||..:..|:.|...|...:.||..||..|.|:..::::||.:...|:|.|.
Human   400 RMHRLEFFP-----KPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFH 459

  Fly   453 MELSPEQAPLRLEAQMVLKAQQ 474
            ::        .|:.|.|...|:
Human   460 VK--------TLQGQCVESIQK 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	104/514 (20%)
CYP19A1	NP_000094.2	CYP19A1	72..485	CDD:410709	99/490 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010