Protein Alignment Cyp311a1 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 499
• Identity: 150/499 - (30%)
• Similarity: 252/499 - (50%)
• Gaps: 42/499 - (8%)

  Fly     6 LLLITLTIWILVRKWTLLRLGSSLPGP---WAFPLLGNAQMVGKLRPEYIFLVFTELRDRFGATY 67
            |||:....:.|.|:| ||:.....|.|   |.|   |:.:..|....:.|..........|.
Mouse    29 LLLVKAVQFYLHRQW-LLKAFQQFPSPPFHWFF---GHEKFKGDQELQEIVSCIENFPSAFP--- 86

  Fly    68 RLRLGPQLWVFLHSAEETRQAL--HDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAF 130
            |...|.:.::.::..:..:..|  .||....|  :..|.|.||.|||:.:|..|.:.||:|||||
Mouse    87 RWFWGSKAYLTVYDPDYMKVILGRSDPKANGA--YRLLAPWIGYGLLLLNGQPWFQHRRMLTPAF 149

  Fly   131 QPQLLRSFAPAIGGHV-------ERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQS 188
            ...:|:.:...:...:       |||     |.:.:.:|:.:.:....||.::..:...:...|
Mouse   150 HYDILKPYVKNMADSIRLMLDKWERL-----ADQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQ- 208

  Fly   189 VD--HSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKEL 251
            ||  :...:||....:.|...|:.|....:|.|::.:...|...:..|:.|...:.||:.|..:|
Mouse   209 VDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQL 273

  Fly   252 LDMGE----PAGRAHNLLDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAK 311
            .|.||    ...|..:.||.||.|:.| |.|:|.:::|.|::||:|.|.|||.:.:|::.||||.
Mouse   274 QDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALAT 338

  Fly   312 FPETQTRLRKELQDVALD-ETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQ-TTQSTEIGGRT 374
            .|:.|.|.|:|:|.:..| .:...|.|:.:||....|||.||||..||...|: :|..|...||:
Mouse   339 HPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRS 403

  Fly   375 YCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP-PAFSYIPFSGGPHVCIGRRYSLL 438
            ...||.:.:::|||.|:.:.:|:|..|.|.|:.|:    :| .:.|::|||||...|||:::::.
Mouse   404 LPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD----SPRHSHSFLPFSGGARNCIGKQFAMS 464

  Fly   439 LMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFLK 482
            .:|::.|..:..|::...|.:.|:.| |::|||::.||.:...|
Mouse   465 ELKVIVALTLLRFELLPDPTRVPMPL-ARLVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	133/432 (31%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	135/448 (30%)