Protein Alignment Cyp311a1 and Cyp46a1

DIOPT Version :9

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 503
• Identity: 130/503 - (25%)
• Similarity: 217/503 - (43%)
• Gaps: 83/503 - (16%)

  Fly    22 LLRLGSS---------------------LPGPWAFP----LLGNA-------QMVGKLRPEYIFL 54
            ||.|||:                     :|||   |    |||:.       :..|::..:
Mouse     5 LLLLGSAVLLAFGLCCTFVHRARSRYEHIPGP---PRPSFLLGHLPYFWKKDEDCGRVLQD---- 62

  Fly    55 VFTELRDRFGATYRLRLGPQLWVFLHSAEETRQAL------HDPTLRKADTFMQLEPLIGNGLL- 112
            ||.:...::|...|:.:..:..|.:.|.|..::.|      .|..:.:|...:..|.|.|.||:
Mouse    63 VFLDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVS 127

  Fly   113 -ISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVT-EPLFAC-LLDA 174
             ..:| .|.:||:::..||....|.|.........|:||..|.|.......|: :.:..| .:|.
Mouse   128 ECDYG-RWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDI 191

  Fly   175 IVDTSMGAQLDTQSVDHSPIIQAFHL-------SSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQ 232
            :...:.|.:.........|:.||..:       |...|.|.|..         :|.|| |::.|.
Mouse   192 LAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPG---------KRKQL-REIRES 246

  Fly   233 LQVIHSQMESVIEKRAKELLDMGE--PAGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFVFAGV 295
            ::::....:..:::| :|.|..||  ||    ::|..:|.|: || :.....:.|...||..||.
Mouse   247 IRLLRQVGKDWVQRR-REALKRGEDMPA----DILTQILKAE-EG-AQDDEVLLDNFVTFFIAGH 304

  Fly   296 DTTTAAMSFVLYALAKFPETQTRLRKELQDVALDET-TDLDALNGLPYLEALIKEVLRLYTIVPT 359
            :|:...::|.:..|::.||...||:.|:.:|...:. .|.:.|..|.||..::||.||||.....
Mouse   305 ETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWG 369

  Fly   360 TGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP-PAFSYIPF 423
            |.|...:.|.|.|........|..:.|.:.....|:.||..|.|:|:    |..|| |.|:|.||
Mouse   370 TFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRF----GPGAPKPRFTYFPF 430

  Fly   424 SGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLK 471
            |.|...|||::::.:.:|::.|:|::..:..|.|.|. ..|:.|..||
Mouse   431 SLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQR-FGLQEQATLK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	125/474 (26%)
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	120/460 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000