Protein Alignment Cyp311a1 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 514
• Identity: 145/514 - (28%)
• Similarity: 222/514 - (43%)
• Gaps: 77/514 - (14%)

  Fly     1 MALWPLLLITLTIWILVRKWT---LLRLGSSLPGPWAFPLLGN--AQMVGKLRPEYIFLVFTE-- 58
            |..|.||..:|.:..|....:   ..:||  :|||...|.||.  |...|          |.|
Mouse     9 METWMLLATSLVLLYLYGTHSHGIFKKLG--IPGPKPLPFLGTILAYQKG----------FWECD 61

  Fly    59 --LRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKA-------DTFMQLEPLIGNGLL-- 112
              ...::|         ::| .|:...:...|:.||.:.|.       .||.........|:|
Mouse    62 IQCHKKYG---------KMW-GLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKK 116

  Fly   113 ---ISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVG--RLGATRGAFLEVTEPLFACLL 172
               ||....|.|.|.||:|.|....|:...|.|....:.||.  |.|...|....:.:...|..:
Mouse   117 AISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSM 181

  Fly   173 DAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQ-RTQLWRDLDEQL--- 233
            |.|..||.|..:|:.:....|.::..   .|||...:.:||..|..:|. .|.::..|:..|
Mouse   182 DVITATSFGVNIDSLNNPQDPFVEKI---KKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSLFPR 243

  Fly   234 QVIH---SQMESVIEKRAKELLDMGEPAGRAHNLLDTLLL--------AKFEGQSLSRREIRDEI 287
            .||.   :.:|.:.|.|.||         :....:|.|.|        .|...::||..||..:.
Mouse   244 DVISFFTTSVERMKENRMKE---------KEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQS 299

  Fly   288 NTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDE--TTDLDALNGLPYLEALIKEV 350
            ..|:|||.:||::|:||.||.||..|:.|.:|:.|: |.||..  ....|.|..:.||:.::.|.
Mouse   300 VIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEI-DAALPNKAPATYDTLLQMEYLDMVVNET 363

  Fly   351 LRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP 415
            ||||.|.....|......||.|.....|..:.|..:.|..|.:|:|:|..|:|||:..::.....
Mouse   364 LRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSIN 428

  Fly   416 PAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-QAPLRLEAQMVLKAQ 473
            | :.|:||..||..|||.|::|:.||:...|:::.|.::...| :.||:|..|.:|:.:
Mouse   429 P-YMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQGLLQPE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	127/442 (29%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	127/444 (29%)