Protein Alignment Cyp311a1 and Cyp19a1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_031836.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Alignment Length: 485
• Identity: 113/485 - (23%)
• Similarity: 204/485 - (42%)
• Gaps: 85/485 - (17%)

  Fly     5 PLLLITLTIWILVRKWTLLRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFL---------VFTELR 60
            |||||   :.:|:..|. ....||:|||      |....:|.|.....||         .:.::.
Mouse    27 PLLLI---MGLLLLIWN-CESSSSIPGP------GYCLGIGPLISHGRFLWMGIGSACNYYNKMY 81

  Fly    61 DRFGATYRLRLGPQLWVFLHSAEET----------RQALHDPTLRKADTFMQLEPLIG---NGLL 112
            ..|         .::|:   |.|||          ....|...:.:..:...|: .||   ||::
Mouse    82 GEF---------MRVWI---SGEETLIISKSSSMFHVMKHSHYISRFGSKRGLQ-CIGMHENGII 133

  Fly   113 ISHG-AHWTRQRRLLTPAFQ-----PQLLRSF---APAIGGHVERLVGRLGATRGAFLEVTEPLF 168
            .::. :.|    |.:.|.|.     |.|:|..   ..:|..|::|| |.:..|.| :::|...:.
Mouse   134 FNNNPSLW----RTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRL-GEVTDTSG-YVDVLTLMR 192

  Fly   169 ACLLDAIVDTSMGAQLDTQSVDHSPIIQA-FHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQ 232
            ..:||......:|..||..::...  ||. |:....||.|..|        .|:.:.|:|..:..
Mouse   193 HIMLDTSNMLFLGIPLDESAIVKK--IQGYFNAWQALLIKPNI--------FFKISWLYRKYERS 247

  Fly   233 LQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLD---TLLLAKFEGQSLSRREIRDEINTFVFAG 294
            ::.:..::..::||:..::    ..|.:..:.:|   .|:.|:..| .|::..:...|...:.|.
Mouse   248 VKDLKDEIAVLVEKKRHKV----STAEKLEDCMDFATDLIFAERRG-DLTKENVNQCILEMLIAA 307

  Fly   295 VDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRLYTIVPT 359
            .||.:..:.|:|..:|::||.:..:.||:..|..|....::.:..|..:|..|.|.:|...:|..
Mouse   308 PDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVVGDRDIKIEDIQNLKVVENFINESMRYQPVVDL 372

  Fly   360 TGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFS 424
            ..|:..:...|.|.....|..:.:|: |..|..||:|.|..|..|.:  |...   |...:.||.
Mouse   373 VMRRALEDDVIDGYPVKKGTNIILNI-GRMHRLEYFPKPNEFTLENF--EKNV---PYRYFQPFG 431

  Fly   425 GGPHVCIGRRYSLLLMKLLTARLVREFQME 454
            .||..|.|:..::::||::...|:|.||::
Mouse   432 FGPRGCAGKYIAMVMMKVVLVTLLRRFQVK 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	95/417 (23%)
Cyp19a1	NP_031836.1	CYP19A1	72..485	CDD:410709	96/430 (22%)