Protein Alignment Cyp311a1 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 505
• Identity: 155/505 - (30%)
• Similarity: 250/505 - (49%)
• Gaps: 51/505 - (10%)

  Fly     1 MALWPLLLITLTIWILVRKWTLLRLGSSLPG-PWAFPLLGNAQMVGKLRPEYI--FLVFTELRDR 62
            ::::|:|:      ...|||..:|   |:|. ..|:||:|:|..:.....|:.  .:.:|| ..|
Mouse    31 ISIFPMLV------SYARKWQQMR---SIPSVARAYPLVGHALYMKPNNAEFFQQLIYYTE-EFR 85

  Fly    63 FGATYRLRLGPQLWVFLHSAEETRQAL-HDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLL 126
            .....:|.:||...|.|:.||.....| ....:.|:..:..|:|.:|.|||.|.|:.|..:|::|
Mouse    86 HLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRKML 150

  Fly   127 TPAFQPQLLRSFAPAIGGHVERLVGRL-----GATRGAFLEVTEPLFACLLDAIVDTSMGAQLDT 186
            ||.|...:|.:|...:......||.:|     ......|..:|    .|.||.|.:|:||..:..
Mouse   151 TPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYIT----LCALDIICETAMGKNIGA 211

  Fly   187 QSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLW-------RDLDEQLQVIHSQMESVI 244
            ||.:.|..::..:..|.::::||..|.|   |.    .||       ||....|:.:|:...:||
Mouse   212 QSNNDSEYVRTVYRMSDMIYRRMKMPWL---WF----DLWYLVFKEGRDHKRGLKCLHTFTNNVI 269

  Fly   245 EKRAKELLDMGEPAGRAHN----------LLDTLL-LAKFEGQSLSRREIRDEINTFVFAGVDTT 298
            .:|.||.....:..|....          .||.|| :...||..||:.:||:|::||:|.|.|||
Mouse   270 AERVKERKAEEDWTGAGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTT 334

  Fly   299 TAAMSFVLYALAKFPETQTRLRKELQDV--ALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTG 361
            .||:::.||.|...||.|.::.:||.:|  .......|:.|..|.||:.:|||.||::..||...
Mouse   335 AAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFA 399

  Fly   362 RQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGG 426
            |..::..|:||.....|....|..|.|..|..|:|||..|:|||:.||:.....| ::|:|||.|
Mouse   400 RSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGRHP-YAYVPFSAG 463

  Fly   427 PHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGI 476
            |..|||::::::..|.:.|.::|:|.:|.:.::..|.|...::|:...||
Mouse   464 PRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLILRPNNGI 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	138/439 (31%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	141/451 (31%)