Protein Alignment Cyp311a1 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 508
• Identity: 127/508 - (25%)
• Similarity: 217/508 - (42%)
• Gaps: 77/508 - (15%)

  Fly     3 LWPLLLITLTIWILVRKWTLLRLGS-------------------SLPGPWAFP----LLGNAQMV 44
            :|..:::....|: ...:.|:.:|:                   .:|||   |    |||:...:
 Frog     1 MWHSVIVHCLSWV-YSGFLLIIIGAVVAFLAYCAYIKYMHLKYDDIPGP---PRDSFLLGHIPTL 61

  Fly    45 GKLRPEY-----IFLVFTELRDRFGATYRLRLGPQLWVFLHSAEETRQAL------HDPTLRKAD 98
            .|....|     :||.:.|:   :|..:::.:..::.::..|.|..::.|      .||.
 Frog    62 SKAEENYSVVHDLFLHWAEI---YGPVFKINILHRVMIYSTSPESVKECLMSSKYPKDPY----- 118

  Fly    99 TFMQL-----EPLIGNGLLI--SHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGAT 156
            |:.||     :..:|.|||.  .|. ||..|||::.|||....|:..........|:::.:|...
 Frog   119 TYNQLFNLFGKRFLGKGLLTDPDHD-HWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEK 182

  Fly   157 RGAFLEVT--EPLFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLL---FKRMINPLLS- 215
            .....||:  ..:....||.|...:.|..|.....:.:....|.   ||:|   .:.|.||.:.
 Frog   183 ADGHQEVSMHSIINRVTLDVITKVAFGMDLGLVEGNKTDFPNAI---SKVLTGMMRYMQNPYMQY 244

  Fly   216 --SDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQSL 278
              ..|.|.     |::.|...::....:..|.:| |:.:..||...:  ::|..:|.......:|
 Frog   245 FPKHWAFV-----REVQESADLLRKTGKECISQR-KKAMQNGEELPK--DILTKILQCAELENAL 301

  Fly   279 SRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDV-ALDETTDLDALNGLPY 342
            ....:.|...||..||.:||...:||.:..|.:.||..|:||.|:.:| ........|.:..|.|
 Frog   302 DDEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGFKRDISYDDIQNLNY 366

  Fly   343 LEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWL 407
            :..::||.||.|...|.|.|...:.|...|.....||::..|.|.:...::::.||..|.|||:.
 Frog   367 MTQVLKESLRFYPPGPGTSRYLKEDTIFEGIKIPGGVSITFNTYVMGRMEKFFQDPCKFDPERFH 431

  Fly   408 PEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQA 460
            |   |...|.|.|.||:.||..|:|:.:|.|..|::.::|::.|:.||.|.|:
 Frog   432 P---AAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEFELVPGQS 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	111/419 (26%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	114/433 (26%)