Protein Alignment Cyp311a1 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 514
• Identity: 137/514 - (26%)
• Similarity: 233/514 - (45%)
• Gaps: 76/514 - (14%)

  Fly     4 WPLLLITLTIWILVRKWTLLRLGS---------SLPGPWAFPLLGNAQMVGKLRPEYIFLVFTEL 59
            |.||.|.|.:        |.|.|:         .:|||...|.||......|    .::....|.
Mouse    12 WVLLAIILVL--------LYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYK----GLWKFDMEC 64

  Fly    60 RDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRK----ADTF------MQLEP--LIGNGLL 112
            .:::|.|:.|..| |:.:|:         :.||.:.|    .:.|      .:..|  ::...:.
Mouse    65 YEKYGKTWGLFDG-QMPLFV---------ITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAIS 119

  Fly   113 ISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRL--GATRGAFLEVTEPLFACLLDAI 175
            ||....|.|.|.||:|.|....|:...|.|..:.:.||..|  .|.:|..:.:.:.|.|..:|.|
Mouse   120 ISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVI 184

  Fly   176 VDTSMGAQLDTQSVDHSPIIQ------AFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQ 234
            ..||.|..:|:.:....|.::      .......|:|..::.|.|:.  :::...:.....:.::
Mouse   185 TSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTP--VYEMLNICMFPKDSIE 247

  Fly   235 ----VIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFVFAGV 295
                .::...||.::.:.|..:|..:....|||....    |...::||..||..:...|:|||.
Mouse   248 FFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKD----KDSHKALSDMEITAQSIVFIFAGY 308

  Fly   296 DTTTAAMSFVLYALAKFPETQTRLRKELQDVALDET------TDLDALNGLPYLEALIKEVLRLY 354
            :||::.:||.||.||..|:.|.:|::|     :|||      ...|.:..:.||:.::.|.||||
Mouse   309 ETTSSTLSFTLYCLATHPDIQKKLQEE-----IDETLPNKAPPTYDTVMEMEYLDMVLNETLRLY 368

  Fly   355 TIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPED-GAVAPPAF 418
            .|.....|...:..|:.|.....|.|:.|..|.|.||.:::|:|..|:|||:..|: |::.|  :
Mouse   369 PIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDP--Y 431

  Fly   419 SYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-QAPLRLEAQMVLKAQQGI 476
            .|:||..||..|||.|::.:.|||...::::.|..:...| |.||:|..|.:|:.::.|
Mouse   432 LYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQPEKPI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	121/445 (27%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	121/447 (27%)