Protein Alignment Cyp311a1 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 507
• Identity: 153/507 - (30%)
• Similarity: 250/507 - (49%)
• Gaps: 58/507 - (11%)

  Fly     6 LLLITLTIWILVRKWTLLRLGSSLPGP---WAFPLLGNAQMVGKLRPEYIFLVFTELRDRFGATY 67
            |||:....:.|.||| ||:.....|.|   |.|   |:.|..|:          .||::......
Mouse    29 LLLVKAVQFYLHRKW-LLKALQQFPSPPFHWFF---GHEQFKGE----------QELKEVVSCIE 79

  Fly    68 RLRLGPQLWVFLHSAEETRQALHDPTLRKA----------DTFMQLEPLIGNGLLISHGAHWTRQ 122
            ........|.:..:|..|   ::||...|.          ..:..|.|.||.|||:.:|..|.:.
Mouse    80 HFPSAFPCWFWGSNAYLT---VYDPDYMKVILGRSDPKANGIYRLLAPWIGYGLLLLNGQPWFQH 141

  Fly   123 RRLLTPAFQPQLLRSFAPAIGGHV-------ERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSM 180
            ||:|||||...:|:.:...:...:       |||.|     :.:.:|:.:.:....||.::..:.
Mouse   142 RRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAG-----QDSSIEIFQHISLMTLDTVMKCAF 201

  Fly   181 GAQLDTQSVD--HSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESV 243
            ..:...| ||  :...:||....:.|...|:.|....:|.|::.:...|...:..|:.|...:.|
Mouse   202 SHKGSVQ-VDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGV 265

  Fly   244 IEKRAKELLDMGE----PAGRAHNLLDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAAMS 303
            |:.|..:|.|.||    ...|..:.||.||.|:.| |.|:|.:::|.|::||:|.|.|||.:.:|
Mouse   266 IKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVS 330

  Fly   304 FVLYALAKFPETQTRLRKELQDVALD-ETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQ-TTQ 366
            ::.||||..||.|.|.|:|:|.:..| .:...|.|:.:||....|||.||||..||...|: :|.
Mouse   331 WIFYALATHPEHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTS 395

  Fly   367 STEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP-PAFSYIPFSGGPHVC 430
            .|...||:...||.:.:::|||.|:.:.:|:|..|.|.|:.|:    :| .:.|::|||||...|
Mouse   396 VTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD----SPRHSHSFLPFSGGARNC 456

  Fly   431 IGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFLK 482
            ||:::::..:|::.|..:..|::...|.:.|..| |::|||::.||.:...|
Mouse   457 IGKQFAMSELKVIVALTLLHFELLPDPTRVPEPL-ARIVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	134/440 (30%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	135/446 (30%)