DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HOXB7 and ftz

DIOPT Version :9

Sequence 1:	NP_004493.3	Gene:	HOXB7 / 3217	HGNCID:	5118	Length:	217	Species:	Homo sapiens
Sequence 2:	NP_477498.1	Gene:	ftz / 40834	FlyBaseID:	FBgn0001077	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	116	Identity:	59/116 - (50%)
Similarity:	75/116 - (64%)	Gaps:	12/116 - (10%)

- Green bases have known domain annotations that are detailed below.

Human   101 PGDSAKAAGAKEQRDSDLAAESNFRIYPW------MRSSGTDRKRGRQTYTRYQTLELEKEFHYN 159
            ||:.:.:|.::|.....:.|.:....:.|      :.|...|.||.|||||||||||||||||:|
  Fly   212 PGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFN 276

Human   160 RYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKEN------KTAGPGTT 204
            ||:||||||:||:.|.|:||||||||||||||.||:.      :..|.|.|
  Fly   277 RYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYT 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		1/10 (10%)
		Homeobox	141..193	CDD:278475	44/51 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..217		4/17 (24%)
ftz	NP_477498.1	FTZ	1..248	CDD:281812	6/35 (17%)
ftz	NP_477498.1	Homeobox	257..310	CDD:278475	44/52 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45659
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910