Protein Alignment Usp7 and UBP12

DIOPT Version :9

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_568171.1
• Gene: UBP12 / 830548
• AraportID: AT5G06600
• Length: 1116
• Species: Arabidopsis thaliana
• Alignment Length: 1165
• Identity: 396/1165 - (33%)
• Similarity: 620/1165 - (53%)
• Gaps: 124/1165 - (10%)

  Fly    36 SPPQL--PKFKNLIQPQLHAVGAVTQLPSENGNMPPQQLLADSSSTSFGDGEAMGIDDESKEDQF 98
            :||.:  |:.:.::.|....|         :|...|.::....::.|       .::::..||.
plant     5 TPPPVDQPEDEEMLVPNSDLV---------DGPAQPMEVTQPETAAS-------TVENQPAEDP- 52

  Fly    99 RSETTFSFTVENVVQLKSQRLSPPVY-VRMLPWRIMVIP---NDRALGFFLQCNGENDSP-TWSC 158
             ....|::|:.|..:..:::....|: |....|||::.|   |...|..:|..:.....| .||.
plant    53 -PTLKFTWTIPNFSRQNTRKHYSDVFVVGGYKWRILIFPKGNNVDHLSMYLDVSDAASLPYGWSR 116

  Fly   159 NAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDSEKSYVHNNSITLEVHVV 223
            .|...|.: .::...:...|...:|.|.::|:|:|:::|:...||.|..:.|:.|:::.:|..|
plant   117 YAQFSLAV-VNQIHTRYTVRKETQHQFNARESDWGFTSFMPLSELYDPSRGYLVNDTVLVEAEV- 179

  Fly   224 ADAPHGVL----WDSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIP-TEADDSSKSV 283
              |...||    :||||.||:||||||||||||||||||||.....|.:||.:| ||.|..:.|:
plant   180 --AVRKVLDYWSYDSKKETGFVGLKNQGATCYMNSLLQTLYHIPYFRKAVYHMPTTENDAPTASI 242

  Fly   284 GLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIP 348
            .|:||.:|::||:.|..|.||:|||||||:|.||||||||||..|||.:|||.|||||::||||.
plant   243 PLALQSLFYKLQYNDTSVATKELTKSFGWDTYDSFMQHDVQELNRVLCEKLEDKMKGTVVEGTIQ 307

  Fly   349 GLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGL 413
            .||||...:||:|.|||:.|||.|:|||:||::|..|::|.||..||..|.|||||||.|..|||
plant   308 QLFEGHHMNYIECINVDFKSTRKESFYDLQLDVKGCKDVYASFDKYVEVERLEGDNKYHAEGHGL 372

  Fly   414 QEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDR----YLA-ESENTLAD 473
            |:|.|||:|..|||||.|.|.||:||.:.|:.:|.|||:||...::|||    ||: :::.::.:
plant   373 QDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLELDLDREDGKYLSPDADRSVRN 437

  Fly   474 -YVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDDEI-----S 532
             |.||:||||||..|||||..||.|....:|:||||:.|:....:.|:|:.||| ::|:     .
plant   438 LYTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKFDDERVTKEDLKRALEEQYGG-EEELPQTNPG 501

  Fly   533 FH-------AKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANT 590
            |:       .|.||||||||||:|:.|:::.::.|.:|:..|..||..|:..:..:|:.:.:|:.
plant   502 FNNNPPFKFTKYSNAYMLVYIRESDKDKIICNVDEKDIAEHLRVRLKKEQEEKEDKRRYKAQAHL 566

  Fly   591 YVSVHVILEENFEEQ-HKRRLFDL---EKVHPRVFRIKQNQTVDELVDLFVRGFGVSRQRMRMWN 651
            |..:.|..:|:.:|| .|...|||   :||  |.|||::.....:..:...:.|||..|..|.|.
plant   567 YTIIKVARDEDLKEQIGKDIYFDLVDHDKV--RSFRIQKQTPFQQFKEEVAKEFGVPVQLQRFWI 629

  Fly   652 LCTAQTQKF---------SHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGPLPPFNPKTES 707
            ....|...:         .....|.:......:.:|::..  ::|::...|:....||...|.:.
plant   630 WAKRQNHTYRPNRPLTPQEELQPVGQIREASNKANTAELK--LFLEVEHLDLRPIPPPEKSKEDI 692

  Fly   708 LLFLKYYDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLV---NLN 769
            |||.|.|||....|:|.|......:.:.:|:...:|..:||.||.|:.:::|...:..|   :|:
plant   693 LLFFKLYDPEKAVLSYAGRLMVKSSSKPMDITGKLNEMVGFAPDEEIELFEEIKFEPCVMCEHLD 757

  Fly   770 EPIESALFIPQDHLQGHILIFERENVDAKLD--LPTVGDYFLDLVYRIEII-FSDKCNPNEPDFT 831
            :.....|...:|   |.|:.|::..|:.:::  .|.|.. ||:.|...::: |.....|.|.:|.
plant   758 KKTSFRLCQIED---GDIICFQKPLVNKEIECLYPAVPS-FLEYVQNRQLVRFRALEKPKEDEFV 818

  Fly   832 LELSNRYNYDQLANAVAERLN-TDPQKLQFFMCINNYKETAGNAVPYTFKGT--IKDLVSYTKQS 893
            ||||.::.||.:...|||:|. .||.||:  :..:|.........|..::|.  :.|::.:..|:
plant   819 LELSKQHTYDDVVEKVAEKLGLDDPSKLR--LTSHNCYSQQPKPQPIKYRGVDHLSDMLVHYNQT 881

  Fly   894 STKRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDEKELVLYPN----KNDTVKGLLEEAAKKISF 954
            | ..::|:.|.:.:.||...|..|..:..:    .||.|:..|    |..||..::.|...|:..
plant   882 S-DILYYEVLDIPLPELQGLKTLKVAFHHA----TKEEVVIHNIRLPKQSTVGDVINELKTKVEL 941

  Fly   955 AENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQLAENEF 1019
            : :...:||||::..|||..:          ..|.|.|........|.|.||:|.|:..:..|:.
plant   942 S-HPDAELRLLEVFYHKIYKI----------FPSTERIENINDQYWTLRAEEIPEEEKNIGPNDR 995

  Fly  1020 LIPVAHFSKEL-----YNSFGIPFLTKARQGEPYGALKQRIQRRLNVQDKEWENYKFCVISMG-- 1077
            ||.|.||:||.     ..:||.||.....:||....:|.|||::|:|.|:::..:||..:|||
plant   996 LILVYHFAKETGQNQQVQNFGEPFFLVIHEGETLEEIKNRIQKKLHVSDEDFAKWKFAFMSMGRP 1060

  Fly  1078 ---HNADVNDNTPVDLEVYRSWTSGQLPFFGLDHINKSRKRS-----SLNFSEKAIKIYN 1129
               .:.||..|.....:||.::..    :.||:|.:.:.||:     :.:..||.:||||
plant  1061 EYLQDTDVVYNRFQRRDVYGAFEQ----YLGLEHADTTPKRAYAANQNRHAYEKPVKIYN 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	32/133 (24%)
		COG5077	101..1119	CDD:227409	380/1086 (35%)
		peptidase_C19C	239..549	CDD:239124	180/328 (55%)
		USP7_ICP0_bdg	647..886	CDD:289221	62/256 (24%)
		USP7_C2	897..1113	CDD:291217	65/229 (28%)
UBP12	NP_568171.1	MATH	55..179	CDD:238068	30/124 (24%)
		COG5077	57..1114	CDD:227409	382/1091 (35%)
		peptidase_C19C	197..526	CDD:239124	180/329 (55%)
		USP7_ICP0_bdg	625..875	CDD:289221	63/257 (25%)
		USP7_C2	884..1095	CDD:291217	65/229 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	332	1.000	Domainoid score	I257
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2592
Inparanoid	1	1.050	568	1.000	Inparanoid score	I242
OMA	1	1.010	-	-		QHG55761
OrthoDB	1	1.010	-	-		D77113at2759
OrthoFinder	1	1.000	-	-		FOG0003101
OrthoInspector	1	1.000	-	-		otm3411
orthoMCL	1	0.900	-	-		OOG6_101317
Panther	1	1.100	-	-	O	PTHR24006
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2073
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840