Protein Alignment Usp7 and faf

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_524612.2
• Gene: faf / 43749
• FlyBaseID: FBgn0005632
• Length: 2778
• Species: Drosophila melanogaster
• Alignment Length: 1066
• Identity: 224/1066 - (21%)
• Similarity: 362/1066 - (33%)
• Gaps: 384/1066 - (36%)

  Fly   232 WD------SKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYR----IPTEADD-------- 278
            ||      ::...|:.||||.||||||||:||.||...::|:.:.|    ..|:.:|
  Fly  1653 WDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLT 1717

  Fly   279 -----------------SSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFG--------------- 311
                             |..|...:::...|:::.....|..|.:...|.
  Fly  1718 GGGLGSALFSGPASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGL 1782

  Fly   312 W-------ETLDSFMQHDVQEFLRVLLDKLESKMKG----TILEGTIPGLFEGKMSSYIKCKNVD 365
            |       |.::...|.|..||...||:.|:..:|.    .::..|:.|.|    |....|:...
  Fly  1783 WTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSF----SDQKICQECP 1843

  Fly   366 YNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQEAS-KGVIFTSFPPVL 429
            :..::.|.|....::|::..::.||.:.||..|.|||.:.|.......:..: |.|.....||||
  Fly  1844 HRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVL 1908

  Fly   430 HLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRY----LAESENTLAD-------------YVLH 477
            .:.|.||:||.....:||:||.|||...::::.|    ||:.|..:.:             |.|.
  Fly  1909 AIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELT 1973

  Fly   478 AVLVHSGDNHGGHYVVFI---NPKADGR--WFKFDDDVVSSCRKQEAIEQN---YGG--MDDEIS 532
            .::||||...||||..:|   || |:|:  |:||||..|:.|:..|..|..   :||  |.:...
  Fly  1974 GIVVHSGQASGGHYFSYILSKNP-ANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYD 2037

  Fly   533 FHAKCS---------NAYMLVYIRQSELDRVLGDITESEISSDLVERLDL-EKR---IEMARRKE 584
            .:.|..         |||||.|.|..:..      .:.|.|   ||:|.| |.|   :.:.:..|
  Fly  2038 NNLKRMQYRRQKRWWNAYMLFYTRCDQTP------VQYEPS---VEQLSLAESRNMVLPLPKPIE 2093

  Fly   585 RGEANTYVSVHVILEENFEEQHKRRLFDLE-------------------KVHPRV---------- 620
            |.          :..:|....|.|.:|.:|                   |:.|..
  Fly  2094 RS----------VRHQNIRFLHSRSIFSVEFFNFIKKLVSCNLLSARSNKITPAAEELSLLGVQL 2148

  Fly   621 ---------FRIKQN-------------------------------------------------- 626
                     ||.|::
  Fly  2149 ASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSRLGEYILMAPSPDV 2213

  Fly   627 QTVDELVDLFVRGFGVSRQRMRMW---NLC--------------TAQTQK-----FSHFD-FVAE 668
            :||...:.:|...|.::.:.:..:   |||              .|...|     ||.|. :|..
  Fly  2214 RTVFVKLVVFFCHFAINDEPLTGYDGANLCEQVLISVLRLLKSEAADYGKHLPHYFSLFSMYVGL 2278

  Fly   669 GSRTIEQISTSQKPWVIWLQLAWTDVPGPLPPFNPKTESLLFLKYYDPRNKRLNYIGCTQQPHTR 733
            |:|..:|:.....| :.::|:|..|.|||.            :||..|...:|:.:    ..|..
  Fly  2279 GTREKQQLLRLNVP-LQFIQVALDDGPGPA------------IKYQYPEFSKLHQV----VSHLI 2326

  Fly   734 RLIDLVPDVNSKLGFEPDTELTIYDEYAD-----KKLVNLNEPIESALFIPQDHLQGHI-LIFER 792
            |    ..||:.|..........:.:.:.|     ::|..|:......||    :..|:| .:.|.
  Fly  2327 R----CSDVSEKCQSSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLF----NRTGYIKKVIED 2383

  Fly   793 ENVDAKLDLPTVGDYFLDLVYRIEIIFSDKCNPNEPDFT-------------------------- 831
            .|         |||..|.|:        ..|:...|.|:
  Fly  2384 TN---------VGDEGLKLL--------QYCSWENPHFSRAVLTELLWQCGFAYCHDMRHHTDLL 2431

  Fly   832 ---LELSNRYNYDQLANA---VAE----------RLNTDPQK--LQFFMCINNYKETAGNAVPYT 878
               |.:.:.:.:.::.||   |||          |..|..||  .|...|:..          ..
  Fly  2432 LNILLIDDSWQHHRIHNALNGVAEEREGLLETIQRAKTHYQKRAYQIIKCLTQ----------LF 2486

  Fly   879 FKGTIKDLVSYTKQSSTKRIFYQRLSLSIH----ELDNKKQFKCVWVSSDLKDEKELVLYPNKND 939
            .|..|...:.:|..:.|:     ..|:::.    |||.::...|.:.|.......:      .||
  Fly  2487 HKSPIALQMLHTNSNITR-----HWSIAVEWLQGELDRQRGIGCQYNSYSWSPPAQ------SND 2540

  Fly   940 TVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVAVCKDDIP----------LDTLLKSNESITT 994
            ...|.:.|.::.   |:|:.          .....:|.|::.          |:|.:..|:|...
  Fly  2541 NTNGYMLERSQS---AKNTW----------SMAFELCPDEVSEKTDENNEPNLETNMDENKSEPV 2592

  Fly   995 AQ--GAQKTFRIEEVPAEDMQLAENE 1018
            ||  |.     :|.......||.||:
  Fly  2593 AQPGGV-----LEGSTGGTEQLPENK 2613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	224/1066 (21%)
faf	NP_524612.2	Ubl1_cv_Nsp3_N-like	<994..1060	CDD:475130
		peptidase_C19C	1666..2064	CDD:239124	111/402 (28%)
		DUF3517	2198..2566	CDD:463438	78/443 (18%)