DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp7 and Usp1

DIOPT Version :9

Sequence 1:	NP_572779.2	Gene:	Usp7 / 32169	FlyBaseID:	FBgn0030366	Length:	1129	Species:	Drosophila melanogaster
Sequence 2:	NP_001263061.1	Gene:	Usp1 / 43462	FlyBaseID:	FBgn0028476	Length:	1078	Species:	Drosophila melanogaster

Alignment Length:	290	Identity:	63/290 - (21%)
Similarity:	95/290 - (32%)	Gaps:	82/290 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 GYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFH-ELQFGDRPVG 302
            |..|.....||.      .:|::.|::.||      .|..:|.|...|...|.. .......|..
  Fly   574 GITGAGTAHATA------NSLFYLNTVDLS------GASSTSGSASTSASGVVSTSAALPTPPQA 626

  Fly   303 TKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGL--------FEGKMSSYI 359
            ||             :...|......||.||:.       ||..|..|        |||.:....
  Fly   627 TK-------------YSSDDEMNSATVLKDKMR-------LEERIRELNLNFFSSDFEGIVVLTT 671

  Fly   360 KCKNVDYNSTRYETFYDIQL----------NIKDKKNIYESFQDYVAPETLEGDNKYDAG-VHGL 413
            ||.:.:..:.:.:...||.:          :::||.:.|.. ...:..|...|:|||... ..|.
  Fly   672 KCLSCETITRQKQGMLDISVPVPISGYDNADLQDKPSTYIQ-NSCITKEYFRGENKYSCNQCTGY 735

  Fly   414 QEASKGVIFTSFPPVLHLHLMRFQ--------YDPVTDSSIKYNDRFEFYEHINLDRYLAE---- 466
            .||.:.:.:...|.:|.:.|.||.        |.|.|               ..|..:.|.
  Fly   736 TEAIRSISYEVLPRLLVIQLNRFSGGMEKVSTYVPTT---------------FTLPCFCATCCEL 785

  Fly   467 -SENTLADYVLHAVLVHSGDN-HGGHYVVF 494
             ..|.|..|.|::|:.|.|.. ..|||:.:
  Fly   786 GEGNKLHVYKLYSVITHVGATLTVGHYIAY 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741
		COG5077	101..1119	CDD:227409	63/290 (22%)
		peptidase_C19C	239..549	CDD:239124	63/290 (22%)
		USP7_ICP0_bdg	647..886	CDD:289221
		USP7_C2	897..1113	CDD:291217
Usp1	NP_001263061.1	Peptidase_C19	308..819	CDD:271592	63/290 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24006
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030