Protein Alignment Usp7 and usp25

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_009303832.2
• Gene: usp25 / 406790
• ZFINID: ZDB-GENE-040426-2847
• Length: 1166
• Species: Danio rerio
• Alignment Length: 1211
• Identity: 215/1211 - (17%)
• Similarity: 360/1211 - (29%)
• Gaps: 515/1211 - (42%)

  Fly    44 KNLIQ--PQLHAVGAVTQLPSENGNMPPQQLLADSSSTSFGDGEAMGIDDESKEDQFRSETTFSF 106
            :|::|  .|.|....:.||....|. ...|||..:...|.||
Zfish     5 QNVLQQHSQKHQQTLLNQLREVTGT-TDVQLLQQALQVSNGD----------------------- 45

  Fly   107 TVENVVQLKSQRLSPPVYVRMLPWRIMVIPNDRALGFFLQCN-------GENDSPTWSCNAIAEL 164
            .||.|..|..:....|.......::...|.|||.:....|.:       |::
Zfish    46 LVEAVAFLTEKNAKVPQQDEATYYQTAQITNDRYISVGSQADTNVIDLTGDD------------- 97

  Fly   165 RLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDS---EKSYVHNNSITLEVH--VVA 224
                 |.|.|     |...|...:.|.......||.:|...|   |.|...|.:.....|  |.:
Zfish    98 -----KDDLQ-----RAIALSLEESNRAFRETGITDEEQAISRVLEASIAENKASLKRTHTEVWS 152

  Fly   225 DAPHGVLWDSKKHTGY-VGLKNQGATCYMNSLLQTLYFTNSL---RLSV-YRIPTEADDSSKSVG 284
            |:|:.  .:.|:.... |||||.|.||:.::::|:|:  |.|   ||.: |..|....|..::
Zfish   153 DSPNP--HERKRMENCPVGLKNVGNTCWFSAVIQSLF--NLLEFQRLVLHYSPPARMQDLPRN-- 211

  Fly   285 LSLQRVFHELQFGDR-------PVGTKK--LTKSFGWETL-DSF-----MQHDVQEFLRVLLDKL 334
               |:....|.|...       .||:|:  :..|...|.| |:|     .|.||.||...|||.|
Zfish   212 ---QKEHRNLPFMQELRHLFSLLVGSKRKYVDPSGAVEILKDAFKSSESQQQDVSEFTHKLLDWL 273

  Fly   335 E-------------SKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKN 386
            |             .|.|..::|     ||.|:..:....:...:.:|  |.|....|.:...|:
Zfish   274 EDAFQIKAEEDREGEKPKNPMVE-----LFYGRFLAVGVLEGKKFENT--EMFGQYPLQVNGFKD 331

  Fly   387 IYESFQDYVAPETLEGDNKYDAGVHGLQEASKG---VIFTSFPPVLHLHLMRFQYDPVTDSSIKY 448
            ::|..:    ...:||:.:   .:|..:.::|.   ..||..||||...|.||:::.......|.
Zfish   332 LHECLE----AAMIEGEIE---SLHSAENSAKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKI 389

  Fly   449 NDRFEFYEHINLDRYL------------------------------------------------- 464
            :::.||...:.:|||:
Zfish   390 HNKLEFPSMLYMDRYMDRNREITRIKREEIRRLKEHLTVLQQRLERYLSYGSGPKRFPLADVLQY 454

  Fly   465 ----------------------------------------------------------------- 464
                                                                             
Zfish   455 AMEFASSKPVCTSPVEDIDTTAPPGGTIAQLPPPASAGEQPDACVSAEGSGSGLQASQQQQQRVS 519

  Fly   465 ---------------------------------------AESENTLAD----------------- 473
                                                   :|.||...|
Zfish   520 IHKPFTQSRVPPDLPMHPAPRHITEEELRVLESCLHRWRSEVENDTRDLQASISRIHRTIELMYS 584

  Fly   474 --------YVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDDE 530
                    |.|||||||.|..:.|||..:|..:...||.|::|..|:....:|.:..::||.
Zfish   585 DKSMMQVPYRLHAVLVHEGQANAGHYWAYIYDRHHQRWMKYNDIAVTKSSWEELVRDSFGGY--- 646

  Fly   531 ISFHAKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSVH 595
                 :.::||.|:||                         |.:|..
Zfish   647 -----RNASAYCLMYI-------------------------DDKKPF------------------ 663

  Fly   596 VILEENFEEQHKRRLFDLEKVHP--RVFRIKQNQTVDELVDLFVRGFGVSRQRMRMWNLCTA--- 655
             :::|.|:::..:.|..|:|:.|  :||....|:       ||.|       .|..|:...|
Zfish   664 -LIQEEFDKETGQMLSGLDKLPPDLKVFVEADNK-------LFER-------EMEEWDALQARKL 713

  Fly   656 QTQKFSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGPLPPFNPKTESLLFLKYYDPRNKR 720
            |.:|.:    :|..:......|.:.:|.             ...|.:|...:......:||
Zfish   714 QQEKLA----LAAAAAAAAAASVAVQPM-------------STEPCSPDNTAPSAAPQHDP---- 757

  Fly   721 LNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTI------YDEYADKKLVNLNEPIESALFIP 779
             .|:  .||.         |..:|| ..:.|||..|      :||.:.:.|:|.:
Zfish   758 -EYM--EQQS---------PSGDSK-HLQEDTERAISKAAAEHDEKSPEALLNTS---------- 799

  Fly   780 QDHLQGHILIFERENVDAKLDLPTVGDYFLDLVYRIEIIFSDKCNPNEPD--------------- 829
                       :..:.|:||.                   ||.|.|.:|:
Zfish   800 -----------QSSHPDSKLT-------------------SDPCPPPDPEQDDPTCPPPGPQRVV 834

  Fly   830 ---------FTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYT--FKGTI 883
                     |.:: |....||.      |.:.| |......|.|...:.......|..  ||..
Zfish   835 EVAIPNVGTFVIQ-SKEGGYDD------EAMMT-PNMQGIIMAIGKSRSVYDKCGPEAAFFKAM- 890

  Fly   884 KDLVSYTKQSSTKRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEE- 947
              .|.||:          .|.|:..:...::.::.          :.::::...|:..|.::|.
Zfish   891 --KVEYTR----------LLRLAQEDTPPERDYRL----------QHVIVFFIHNEAPKKIVERT 933

  Fly   948 -----AAKKISFAENSRRKLRLLKISNHKIVAVCKDDIPLD 983
                 |.:.:.|.|..:   .::|::..|:..:..|::.::
Zfish   934 LLMQFADRNLGFDERCK---SIMKVARAKLELIKPDEVNME 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	202/1152 (18%)
usp25	XP_009303832.2	None