Protein Alignment Usp7 and Usp15-31

DIOPT Version :9

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Alignment Length: 946
• Identity: 182/946 - (19%)
• Similarity: 312/946 - (32%)
• Gaps: 280/946 - (29%)

  Fly   229 GVLWDSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLR----LSVYRIPTEADD--SSKSVGL-- 285
            |..|.:.:..|.:||||.|.||:||::||.|..|:.|.    |..|:...:..:  :|:..|.
  Fly   253 GYQWPADQTPGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFGTKG 317

  Fly   286 ----SLQRVFHEL----QFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLE------S 336
                .|..|...|    ...|.....|.:...:|.: ..|..|||.||||..||||:.      |
  Fly   318 ELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQ-FRSSTQHDAQEFLFWLLDKVHEDLNTAS 381

  Fly   337 KMKGTILEGT-----------------------IPGLFEGKMSSYIKCKNVDYNSTRYETFY--D 376
            |.:...|:.:                       :..:|:.:..|.:.|...:..|..::.|:  .
  Fly   382 KRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCIS 446

  Fly   377 IQLNIKDKKNIYESF-------------------QDYVAPETLEGDNKYDAGVHGLQEASKGVI- 421
            :||....::.|:.:.                   ...||   |....:.|.|:.|    |:.|:
  Fly   447 VQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVA---LREQLQADTGIEG----SRMVLV 504

  Fly   422 ------FTSFPPVLHLHLMRFQYD--PV-TDSSIKYNDRFEFYEHINLDRYLAESE--------- 468
                  ||           |..||  || |.|||:.....|......:.:....||
  Fly   505 DLNAEGFT-----------RVFYDTQPVETLSSIETIYCIEVPAATPVAKAATPSETGDKSAPTA 558

  Fly   469 --------NTLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYG 525
                    .:.||.:|....|:...: |.....|..|        |.......|..|:..::...
  Fly   559 VTPSPAAAQSQADLLLLVANVYRAKD-GADITRFGAP--------FSMKAPRDCSYQDLQKRMLR 614

  Fly   526 GM-----DDEISFHAKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKER 585
            .|     .:..|:....:..:.:         |:.....:.:...:.||...|.:.|:||.....
  Fly   615 EMAPLLKPEVFSYATPLAEMFRI---------RLQDPSADPDTYLEQVEHPLLTEMIDMALSVLS 670

  Fly   586 GEANTYVSVHVILEENFEEQH---KRRLFDLEKV---HPRVFRIKQNQ-------TVDELVDLFV 637
            .||... .:.::||.:..|.|   |::  |.|:.   |..|.|:..::       |:::.::.:.
  Fly   671 SEAGPQ-HIKLLLEWSSPEAHFISKQQ--DTEEAVVEHESVARLSASKPSDTAALTLEQCLEHYT 732

  Fly   638 RGFGVSRQ----------------RMRMWNLCTAQTQKFSHFDFVAEGSRTIEQISTSQKPWVIW 686
            :...:|.:                .:.:|:|.......|..|           :...|:.|....
  Fly   733 KAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRF-----------RQHQSKGPQAAK 786

  Fly   687 LQLAWTDVPGPLPPFNPKTESLLFLKYYDPRNKRLNY-------IGCTQQPHTR-RLIDLVPDVN 743
            |.   |.|..||..|:....  |....::..:..|..       :|....|..: |.:|   ..:
  Fly   787 LT---TMVKFPLTAFDMSPH--LARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVD---SRS 843

  Fly   744 SKLGFEPDTELTIYDEYA----------------------DKKLVNLNEPIESALFIPQDHL--- 783
            |.|....|.:.|.||.||                      |::....::...|.  :|:|.:
  Fly   844 STLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSK--VPEDDIEQD 906

  Fly   784 ----QGHILIFERENVDA---KLDLPTVGDYFLDLVYRIEIIFSDKCN-----PNEPDFTLELSN 836
                :.::|.::|.:|||   .......||::   |.||....|...:     ..|| ..||.:.
  Fly   907 IINNEAYMLFYQRRSVDAGECSGSSSNSGDHW---VSRIAPASSSSASSTSGKEREP-VKLEENT 967

  Fly   837 RYNYDQLANAVAERLNTDPQKLQFFMCINNYKETAG--------NAVPYTFK------------- 880
            .   ...|..|.|:..:.|..:   :|.:..|.||.        ..||:..:
  Fly   968 E---SPAAVEVTEKAQSKPVDI---VCQDKAKGTADGPDADQEQTTVPHDLQIEELAFADADVDT 1026

  Fly   881 ---GTIKDLVSYTKQSSTKRIFYQRLSLSIHELD-------NKKQFKCVWVSSDLK---DEKELV 932
               .|||..|:...:...|::..:. :..|..:|       .:|:.:||....:|.   |..||.
  Fly  1027 SLGETIKAEVNLAAKDEPKKVEVEE-ATPIFAMDEDGSEARQEKKEECVKKEDELSEAPDVSELT 1090

  Fly   933 LYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKIS 968
            .....|..|......::.:.|.  :||...|.|..|
  Fly  1091 AESKTNGHVSSSSSSSSSESSL--SSRSSPRSLSTS 1124

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	182/946 (19%)
		COG5077	101..1119	CDD:227409	182/946 (19%)
		peptidase_C19C	239..549	CDD:239124	82/407 (20%)
		USP7_ICP0_bdg	647..886	CDD:289221	58/307 (19%)
		USP7_C2	897..1113	CDD:291217	17/82 (21%)
Usp15-31	NP_611959.2	Peptidase_C19	<262..>383	CDD:271592	38/121 (31%)
		Peptidase_C19	266..>461	CDD:271592	47/195 (24%)
		Peptidase_C19R	<713..918	CDD:239139	33/225 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930