Protein Alignment Usp7 and DUBAI

DIOPT Version :9

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_610784.1
• Gene: DUBAI / 36361
• FlyBaseID: FBgn0033738
• Length: 852
• Species: Drosophila melanogaster
• Alignment Length: 623
• Identity: 144/623 - (23%)
• Similarity: 229/623 - (36%)
• Gaps: 203/623 - (32%)

  Fly   120 SPPVYVRMLPWRIMVIPNDRALGFFLQCNGENDSPTWSCNAIAELRLKCHKPDAQ--PFTRARIK 182
            :|.|:.::|| ||     .|.|.:.     :|.|.|     :.|:.|:..|...|  ..|.|.:.
  Fly   264 TPEVFHKILP-RI-----PRVLQYV-----KNQSTT-----MDEIGLETKKCLQQLVDLTSALML 312

  Fly   183 HLFYSKENDYGYSNFITWQELKDSEKSYVHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQG 247
            . ||.::..|    ..|.:.|:..|.|   .|.:.|     |.|.|.......:....|||.|.|
  Fly   313 R-FYDQDELY----VATKKALQTYEPS---PNCVAL-----AKAMHENAQPWGRRNARVGLVNLG 364

  Fly   248 ATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGW 312
            .||||||:||.|..|:.....:..|...:....| |...:..:.|.|::...|......|:.
  Fly   365 NTCYMNSVLQALAMTSDFSRQILLIECNSVLLMK-VQQQIALMHHSLRYELTPSRVLNATRP--- 425

  Fly   313 ETLDSF---MQHDVQEFLRVLLDKL------ESKMKG----------------------TILEGT 346
               .||   :|.|..|||..|||.|      .|.:.|                      .:..|.
  Fly   426 ---PSFTPGLQQDSSEFLGYLLDLLHEHEINSSSVTGHSVGPPKTGREVDDVPALLSEDILSSGV 487

  Fly   347 IP----------------------------------GL-------------------FEGKMSSY 358
            ||                                  ||                   |.||:|:.
  Fly   488 IPYNSKDHELSSGSNSDNCNHKPTPTPPATPTKATNGLKQQGQQVDQAKPPSTIDKTFAGKLSTT 552

  Fly   359 IKCKNVDYNSTRYETFYDIQLNIKDKK--------NIYESFQDYVAPETLEGDNKY--------- 406
            .:|.|..:.|...::|.::||:..|.|        ::.:..:.|.:||.|:|||:|
  Fly   553 YRCLNCGWESRNEDSFRELQLSFPDDKEDCGATNYSVQDLIEYYCSPEKLDGDNQYFCPQCKKLC 617

  Fly   407 DAGVH-GLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYL------ 464
            ||..| |:.:|.|.:|.|         |.:|:||.      ||:.|.:....:..|..:
  Fly   618 DAERHIGVTQAPKNLILT---------LKQFKYDQ------KYHFRTKLMHKVFHDESVTVKMSA 667

  Fly   465 --AESENTLADYVLHAVLVHSG-DNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQE-------- 518
              :..|.:...|.|:|.:||:| ....|||..|...:|. .|:||:|:||:..:.:|
  Fly   668 KDSLQEMSTVHYDLYAGVVHAGYSMDSGHYFTFAADQAK-NWYKFNDNVVTHSKPEEMHNLTSPN 731

  Fly   519 ----AIEQNYGGMDDEISFHAKCSNAYM------LVYI------RQSELDRVLGDIT--ESEISS 565
                ...:..|..::..|..|.||::.:      :|.:      :..||.|.|.|..  ::.:.:
  Fly   732 TPYILFYKMCGHSNESNSVTASCSSSMVSGSNDQVVSVPLSPPLKLEELPRRLRDYVRKDNHVYN 796

  Fly   566 DLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFE 603
            :       |.:::..:|...|..|.:||.|     ||:
  Fly   797 E-------ELKMQRFKRGNSGHGNAFVSRH-----NFD 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	28/110 (25%)
		COG5077	101..1119	CDD:227409	144/623 (23%)
		peptidase_C19C	239..549	CDD:239124	101/444 (23%)
		USP7_ICP0_bdg	647..886	CDD:289221
		USP7_C2	897..1113	CDD:291217
DUBAI	NP_610784.1	UCH	358..738	CDD:278850	95/402 (24%)
		Peptidase_C19H	359..739	CDD:239129	94/402 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456881
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940