Protein Alignment Usp7 and Usp7

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_063125353.1
• Gene: Usp7 / 360471
• RGDID: 1306915
• Length: 1161
• Species: Rattus norvegicus
• Alignment Length: 1139
• Identity: 534/1139 - (46%)
• Similarity: 741/1139 - (65%)
• Gaps: 86/1139 - (7%)

  Fly    34 RNSPPQLP------KF-------KNLIQPQLHAVG---AVTQLPSENGNMPPQQLLADSSSTSFG 82
            |.:||::|      ||       .:.|:.|.....   .:||.|..|||:            :..
  Rat    36 RYTPPEVPSTSFITKFILVNCPWNDSIENQAGDTDDPPRITQNPVINGNV------------ALS 88

  Fly    83 DGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVYVRMLPWRIMVI-------PNDRA 140
            ||.:...:|...:..:|||.||.||||...:|....||||.:||.|||:|||:       |:.::
  Rat    89 DGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKS 153

  Fly   141 LGFFLQCNGENDSPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKD 205
            :|||||||.|:||.:|||:|.|.|::..::.|.:.|:| ||.|||:.||||:|:|||:.|.|:.|
  Rat   154 VGFFLQCNAESDSTSWSCHAQAVLKIINYRDDDKSFSR-RISHLFFHKENDWGFSNFMAWSEVTD 217

  Fly   206 SEKSYVHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVY 270
            .||.::.::.:|.||.|.|||||||.||||||||||||||||||||||||||||:|||.||.:||
  Rat   218 PEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY 282

  Fly   271 RIPTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLE 335
            .:|||.|||||||.|:|||||:|||..|:||||||||||||||||||||||||||..|||||.:|
  Rat   283 MMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVE 347

  Fly   336 SKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETL 400
            :|||||.:|||||.||.|||.|||:||.|||.|.|.|.:|||||:||.||||:|||.||||.|.|
  Rat   348 NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQL 412

  Fly   401 EGDNKYDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLA 465
            :||||||||.||||||.|||.|.:.||||||.||||.|||.||.:||.||||||.|.:.||.:|.
  Rat   413 DGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 477

  Fly   466 ESE-NTLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDD 529
            ::: ...|:|:||||||||||||||||||::|||.||:|.||||||||.|.|:||||.||||.||
  Rat   478 KTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDD 542

  Fly   530 EISFHAKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSV 594
            ::|.. .|:|||||||||:|:|..||..:|:.:|...|||||..|||||..:||||.||:.|:.|
  Rat   543 DLSVR-HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQV 606

  Fly   595 HVILEENFEEQHKRRLFDLEKVHPRVFRIKQNQTVDELVDLFVRGFGVSRQRMRMWNLCTAQ--T 657
            .::.|:.|.......::|.|||...||::.:|.::.|.|....:..|..:.::|:|.:....  |
  Rat   607 QIVAEDQFCGHQGNDMYDEEKVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGT 671

  Fly   658 QKFSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVP---GPLPPFNPKTESLLFLKYYDPRNK 719
            ::.:..|..|:||:|:.::|.::.||.|:|:....::.   ..||.|:...:.:||||.|||:.:
  Rat   672 KRPAMLDNEADGSKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTR 736

  Fly   720 RLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNEPI-------ESALF 777
            .|||.|....|.:.::.||:|.:..:.||..||.|.:|:|...    ||.|.|       :.||
  Rat   737 SLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKP----NLTERIQDYDVSLDKAL- 796

  Fly   778 IPQDHLQGHILIFERENVD-AKLDLPTVGDYFLDLVYRIEIIFSDKCNPNEPDFTLELSNRYNYD 841
              .:.:.|.|::|::::.: ...:|||..:||.||.:|:::||.||..||:|.|.:.||||.||.
  Rat   797 --DELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYF 859

  Fly   842 QLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLS 906
            |:|..||:||||||..||||.. ..|::..||.:.:.::||::||:.:.|....|:::||:|.:.
  Rat   860 QVAKTVAQRLNTDPMLLQFFKS-QGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMK 923

  Fly   907 IHELDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHK 971
            |.:.:|::.|||:|::|..::| |:.|||:|:..|:.||||..|.:...:.:..:||||:|.::|
  Rat   924 ITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGDKASGRLRLLEIVSYK 987

  Fly   972 IVAVCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQL-AENEFLIPVAHFSKELYNSFG 1035
            |:.|.::|..|:.|         :....:||||||:|.:.:.: .|||.||.||||.||::.:||
  Rat   988 IIGVHQEDELLECL---------SPATSRTFRIEEIPLDQVDIDKENEMLITVAHFHKEVFGTFG 1043

  Fly  1036 IPFLTKARQGEPYGALKQRIQRRLNVQDKEWENYKFCVISMGHNADVN-DNTPVDLEVYRS---- 1095
            ||||.:..|||.:..:.:|||..|::|:||:|.:||.::.||.:..:| |...|:|:.:..
  Rat  1044 IPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGK 1108

  Fly  1096 --------WTSG---QLPFFGLDHINKSRKRSSL 1118
                    |:.|   ..|..|..|..:|....:|
  Rat  1109 RLSGVAVLWSVGLETVQPLGGSSHGIRSISNGAL 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	515/1056 (49%)
Usp7	XP_063125353.1	None