Protein Alignment Usp7 and Usp24

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_001258135.1
• Gene: Usp24 / 313427
• RGDID: 1306799
• Length: 2617
• Species: Rattus norvegicus
• Alignment Length: 986
• Identity: 218/986 - (22%)
• Similarity: 348/986 - (35%)
• Gaps: 309/986 - (31%)

  Fly   233 DSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHELQFG 297
            ||:..:|:|||:|.|||||||::.|.||....|..|:..:..:.|:...||...:|.:|..|...
  Rat  1678 DSRSISGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMES 1742

  Fly   298 DR----PVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSY 358
            ..    |....|:.|.:..| |....|.|..||...|:|:::..:|....|......|:|..|..
  Rat  1743 KLQYYVPENFWKIFKMWNKE-LYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQ 1806

  Fly   359 IKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQE---ASKGV 420
            ..||:..:...|.|.|..:.|.:...:::..|...:|..|.|||.|.|..  ...:|   ..|..
  Rat  1807 KICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYC--EKCKEKRITVKRT 1869

  Fly   421 IFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRY---------------------- 463
            ...|.|.||.:|||||.:|..:..||||:::..|...:|::.|
  Rat  1870 CIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMD 1934

  Fly   464 ----------LAESENTLADYVLHAVLVHSGDNHGGHYVVFINPK---ADGRWFKFDDDVVSSC- 514
                      :|.:||    |.|..|:||||..|.|||..||..:   ..|:|:||:|.|:...
  Rat  1935 QGGGGSPRKKVALTEN----YELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFD 1995

  Fly   515 RKQEAIE-QNYGG-----MDDEIS----FHAKCSNAYMLVY-------------------IRQSE 550
            ...|.:| :.:||     :.|:.:    ...:..|||||.|                   :||..
  Rat  1996 LNDETLEYECFGGEYRPKVYDQTNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEA 2060

  Fly   551 LDRVLGDITESEISSDLV--------ERLD-LEKRIEMARRK----ERGEANTYVSVHVILEENF 602
            .|..|...:..|||....        :||. |.|.::...:|    |:..|..|   .::.:||.
  Rat  2061 EDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIY---QMVRDENL 2122

  Fly   603 EEQHKRRLFDLEKV---------------HPR-------------------VFRIKQNQTVDE-- 631
            :....|.::..:..               ||.                   ..|.|:...||.
  Rat  2123 KFMKNRDVYSSDYFSFVLSLASLNATKLKHPHYPCMAKVSLQLAVQFLFQTYLRTKKKLRVDTEE 2187

  Fly   632 ------------------LVDLFVRGFGVSRQRMRMWNL-CTAQTQKFS-------HFD---FVA 667
                              ||:.|:...|  |:.::::.| |:.:..:.:       ..|   |..
  Rat  2188 WIATIEALLSKSLDACQWLVEYFISSEG--RELVKVFLLECSVREVRVAVATILEKTLDSALFYQ 2250

  Fly   668 EGSRTIEQISTSQKPWVIWLQLAWTDVPGP-------LPPFNPKTESL------LFLKYYDPRNK 719
            :..:::.|:..      :.|.|...|||..       ...||...:..      |.|::...|:.
  Rat  2251 DKLKSLHQLLE------VLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHM 2309

  Fly   720 RLNYIGCTQQ------------------PHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLV 766
            ....:|.:||                  .:|..|:.|..||:|:....|.             :.
  Rat  2310 ISFLLGVSQQNSQIRRWSSAQAREFGNLHNTVALLVLHTDVSSQRNVAPG-------------IF 2361

  Fly   767 NLNEPIESALFIPQDHLQGHILIFERENVDAKLDLPTVGDYFLDLVYRIE------------IIF 819
            ....||..|...|        |:...|.|:|.|.|.....|.|::::.:.            :::
  Rat  2362 KQRPPISVAPSSP--------LLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVY 2418

  Fly   820 SDKCNPNEPDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGT-- 882
            ...||.:. .||:                         |.|   |.|..||   |.|:..|.|
  Rat  2419 CCFCNEHF-SFTM-------------------------LHF---IKNQLET---APPHELKNTFQ 2451

  Fly   883 -------IKDLVSYTKQSSTKRIFYQR---LSLSIH--ELDNKKQFKCVWVSSDLKDEKELVLYP 935
                   ::|.:...:   .|.:|...   |:|..|  .:|:.:.::||         |.||...
  Rat  2452 LLHEILVMEDPIQVER---VKFVFETENGLLALMHHSNHVDSSRCYQCV---------KFLVTLA 2504

  Fly   936 NKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESITTAQGAQK 1000
            .|....|...:|.:...|:|....:|    |:|.|....            :||.|..|:.|  |
  Rat  2505 QKCPAAKEYFKENSHHWSWAVQWLQK----KMSEHYWTP------------QSNVSNETSTG--K 2551

  Fly  1001 TFRIEEVPAED 1011
            ||: ..:.|:|
  Rat  2552 TFQ-RTISAQD 2561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	218/986 (22%)
Usp24	NP_001258135.1	UBA_UBP24	6..42	CDD:270472
		Ubl_UBP24	952..1030	CDD:340585
		peptidase_C19C	1684..2041	CDD:239124	105/363 (29%)