Protein Alignment Usp7 and ubp5

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_588211.1
• Gene: ubp5 / 2539385
• PomBaseID: SPCC188.08C
• Length: 1108
• Species: Schizosaccharomyces pombe
• Alignment Length: 1111
• Identity: 347/1111 - (31%)
• Similarity: 542/1111 - (48%)
• Gaps: 145/1111 - (13%)

  Fly   104 FSFTVENVVQLKSQRLSPPVYVRMLPWRIMVIPND--RALGF------FLQCNGENDSPTWSCNA 160
            |::.:::..:|..:.:||...|....::|...|..  ::.||      ::....|..|..:.|
pombe    58 FTWHIKSWHELDRRAVSPQFAVGSRQFKITYFPQGTLQSAGFTSIFLEYIPSEEEKLSNKYGC-- 120

  Fly   161 IAELRLKCHKPDAQPFTRARIKHLFYSKE-NDYGYSNFITWQEL----KDSEKSYVHNNSITLEV 220
            ..:.......|.....:.|...|..:|.| .|:|::.|...::|    .......|.:.::.|..
pombe   121 CCQFAFVISNPRKPSLSVANSAHCRFSPEIVDWGFTQFAELKKLLCRQAPDVPPIVEDGALLLTA 185

  Fly   221 HV-VADAPHGVLW------DSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADD 278
            :| :...|.||||      |||..||||||||||||||||||||:||..::.|..||:|||::..
pombe   186 YVRILKDPTGVLWHSFNDYDSKIATGYVGLKNQGATCYMNSLLQSLYIIHAFRRIVYQIPTDSPQ 250

  Fly   279 SSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTIL 343
            ...|:..:|||.|:.|||.:.||.|.:|||||||::||||||||||||.|||.|.||..|:.|.:
pombe   251 GKDSIAYALQRCFYNLQFMNEPVSTTELTKSFGWDSLDSFMQHDVQEFNRVLQDNLERSMRDTKV 315

  Fly   344 EGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDA 408
            |..:..||.|||.|||.|.||::.|.|.|.::|||||:|..||:.:||:.|:..|||||||.|.|
pombe   316 ENALTNLFVGKMKSYIACVNVNFESARSEDYWDIQLNVKGMKNLEDSFRSYIQVETLEGDNCYFA 380

  Fly   409 GVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLA----ESEN 469
            ..:|.|||.|||||.||||:|||.|.||:||...|..||.|||:||....:...:|:    :|:|
pombe   381 DTYGFQEAKKGVIFESFPPILHLQLKRFEYDFERDMMIKINDRYEFPLEFDAKAFLSPEADQSQN 445

  Fly   470 TLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDDEISFH 534
              .:|||:.|||||||.|.|||...:..:.||.|:|:||..|:....:|.:|:||||   :...|
pombe   446 --CEYVLYGVLVHSGDLHNGHYYALLKTEKDGPWYKYDDTRVTRATLREVLEENYGG---DYIMH 505

  Fly   535 ---------AKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANT 590
                     .:..:||||:|:|:.:||.::..::..||...|.|.|:...::...|||||.|::.
pombe   506 PPFRSPVKLKRFMSAYMLLYLRKDKLDELMNPVSADEIPEHLKEALNPSIQLAELRRKERLESHL 570

  Fly   591 YVSVHVILEENFEEQHKRRLFDL--------EKVHPRVFRIKQNQTVDELVDLFVRGFGVSRQRM 647
            |..|.:|..|.:.|.|:   ||:        |:..|: ||||:.....|.:.:.....|..::.|
pombe   571 YTKVQLITPEFYSEHHE---FDIADFGNAYKEETIPQ-FRIKKEAKFSEFIPIVAEKLGYPQECM 631

  Fly   648 RMWNL-----CTAQTQKFSHFDFVAEGSRTIEQISTSQKPW-----VIWLQLAWTDVPGPLPPFN 702
            |.|.:     ||.:.:     ..|.|.:.|:|::   :..|     ::.|.|..|       |.|
pombe   632 RFWYVVKRHNCTVRVE-----SPVNELNSTMEEV---KNVWNSQGEILRLYLEIT-------PEN 681

  Fly   703 PKTESL-----------LFLKYYDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTI 756
            ..:.||           :|:||:|.:::.::..|......:..:..:.|.:..:.....:|.|.|
pombe   682 ELSSSLTHQNTGEWNAFIFVKYFDRKSQEISGCGTLHVNKSDEIRSICPLLCERANLPKNTPLNI 746

  Fly   757 YDEYADKKLVNLNEPIESALFIPQDHLQGHILIFE------------RENVDAKLDLPTVGDY-F 808
            |:|.....:..|.  :|.. |...:...|.|:.||            ....|:.|.|     | |
pombe   747 YEEIKPGMVDFLR--LEKT-FTQSELSTGDIICFEPCRPSALEDDIVNSGFDSALKL-----YDF 803

  Fly   809 LD----LVYRIEIIFSDKCNPNEPDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNYKE 869
            |.    :::|...|..|..    .:|.:.|..|..||.|...:.::|......::...| |....
pombe   804 LSNKVLVLFRPRFIDQDSI----IEFEMLLDRRIKYDDLCIELGQKLGIGADHIRLTTC-NPLTY 863

  Fly   870 TAGNAVPYTFKGTIKD-LVSYTKQSSTKRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDEKELVL 933
            :||..||.....|:.: |.|..::..:..|||:.:.:|:.:||.|:..:..|:...|.:.:.:..
pombe   864 SAGMVVPNDSNITLYEILYSSEEEMPSNVIFYETMDVSLSDLDRKRLVRLRWLVDGLANIELVEA 928

  Fly   934 YPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISN---HKIVAVCKDDIPLDTLLKSNESITTA 995
            |.||:..:..|.....::...::..::|:|:.::..   |:       |:.|.||:::.....|.
pombe   929 YINKSGDINDLFGAVCERFPDSDLRKKKVRVYEVFESRYHR-------DLSLRTLIRTINPAATL 986

  Fly   996 QGAQKTFRIEEVPAEDMQLAENEFLIPVAHFSKELYNSFGIPFLTKARQGEPYGALKQRIQRRLN 1060
            .|       |.||.:.:||...|.::.|.||.|::....||||....:..|.:...|.|:..|..
pombe   987 VG-------EVVPLDQLQLYPEEKIVQVHHFHKDIARIHGIPFSFVIKPQEKFIDTKLRLAARTQ 1044

  Fly  1061 VQDKEWENYKFCVISMGHNADV--NDNTPVDLEVYRSWTSGQLPFFGLDHINKSRKRSSLNFSEK 1123
            ..:..:...||||:...:|..|  ||. .:..:|... .:|.|   .||...|..|:.  |..::
pombe  1045 YPESIFSVIKFCVVDFDNNRVVYLNDE-DITYDVVEK-LNGTL---ALDRAKKDSKKP--NILDR 1102

  Fly  1124 AIKIYN 1129
            ||::.|
pombe  1103 AIQMKN 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	343/1099 (31%)
ubp5	NP_588211.1	COG5077	15..1107	CDD:227409	346/1108 (31%)