Protein Alignment Usp7 and Usp7

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_006522201.1
• Gene: Usp7 / 252870
• MGIID: 2182061
• Length: 1143
• Species: Mus musculus
• Alignment Length: 1161
• Identity: 548/1161 - (47%)
• Similarity: 758/1161 - (65%)
• Gaps: 85/1161 - (7%)

  Fly    22 ILTSDLQQTQQQ-----------RNSPPQLP------KFKNLIQPQLHAV----------GAVTQ 59
            |||.|.....|.           |.:||::|      ||..:..|....:          ..:||
Mouse    15 ILTQDTIYFPQSNIISELLPWYLRYTPPEVPSTSVITKFILVNCPWNEGIEYQAGDTDDPPRITQ 79

  Fly    60 LPSENGNMPPQQLLADSSSTSFGDGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVY 124
            .|..|||:            :..||.:...:|...:..:|||.||.||||...:|....||||.:
Mouse    80 NPVINGNV------------TLSDGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCF 132

  Fly   125 VRMLPWRIMVI-------PNDRALGFFLQCNGENDSPTWSCNAIAELRLKCHKPDAQPFTRARIK 182
            ||.|||:|||:       |:.:::|||||||.|:||.:|||:|.|.|::..::.|.:.|:| ||.
Mouse   133 VRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDDKSFSR-RIS 196

  Fly   183 HLFYSKENDYGYSNFITWQELKDSEKSYVHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQG 247
            |||:.||||:|:|||:.|.|:.|.||.::.::.:|.||.|.|||||||.||||||||||||||||
Mouse   197 HLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQG 261

  Fly   248 ATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGW 312
            ||||||||||||:|||.||.:||.:|||.|||||||.|:|||||:|||..|:|||||||||||||
Mouse   262 ATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGW 326

  Fly   313 ETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDI 377
            |||||||||||||..|||||.:|:|||||.:|||||.||.|||.|||:||:|||.|.|.|.:|||
Mouse   327 ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKDVDYRSDRREDYYDI 391

  Fly   378 QLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVT 442
            ||:||.||||:|||.||||.|.|:||||||||.||||||.|||.|.:.||||||.||||.|||.|
Mouse   392 QLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQT 456

  Fly   443 DSSIKYNDRFEFYEHINLDRYLAESE-NTLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWFKF 506
            |.:||.||||||.|.:.||.:|.::: ...|:|:||||||||||||||||||::|||.||:|.||
Mouse   457 DQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF 521

  Fly   507 DDDVVSSCRKQEAIEQNYGGMDDEISFHAKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERL 571
            ||||||.|.|:||||.||||.||::|.. .|:|||||||||:|:|..||..:|:.:|...|||||
Mouse   522 DDDVVSRCTKEEAIEHNYGGHDDDLSVR-HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERL 585

  Fly   572 DLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLEKVHPRVFRIKQNQTVDELVDLF 636
            ..|||||..:||||.||:.|:.|.::.|:.|.......::|.|||...||::.:|.::.|.|...
Mouse   586 QEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVRYTVFKVLKNSSLAEFVQSL 650

  Fly   637 VRGFGVSRQRMRMWNLCTAQ--TQKFSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVP---G 696
            .:..|..:.::|:|.:....  |::.:..|..|:|::|:.::|.::.||.|:|:....::.   .
Mouse   651 SQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGA 715

  Fly   697 PLPPFNPKTESLLFLKYYDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYA 761
            .||.|:...:.:||||.|||:.:.|||.|....|.:.::.||:|.:..:.||..||.|.:|:|..
Mouse   716 TLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVK 780

  Fly   762 DKKLVNLNEPI-------ESALFIPQDHLQGHILIFERENVD-AKLDLPTVGDYFLDLVYRIEII 818
            .    ||.|.|       :.||   .:.:.|.|::|::::.: ...:|||..:||.||.:|:::|
Mouse   781 P----NLTERIQDYDVSLDKAL---DELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVI 838

  Fly   819 FSDKCNPNEPDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTI 883
            |.||..||:|.|.:.||||.||.|:|..||:||||||..||||.. ..|::..||.:.:.::||:
Mouse   839 FCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKS-QGYRDGPGNPLRHNYEGTL 902

  Fly   884 KDLVSYTKQSSTKRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEA 948
            :||:.:.|....|:::||:|.:.|.:.:|::.|||:|::|..::| |:.|||:|:..|:.||||.
Mouse   903 RDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEEC 966

  Fly   949 AKKISFAENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQ 1013
            .|.:...:.:..:||||:|.::||:.|.::|..|:.|         :....:||||||:|.:.:.
Mouse   967 KKAVELGDKASGRLRLLEIVSYKIIGVHQEDELLECL---------SPATSRTFRIEEIPLDQVD 1022

  Fly  1014 L-AENEFLIPVAHFSKELYNSFGIPFLTKARQGEPYGALKQRIQRRLNVQDKEWENYKFCVISMG 1077
            : .|||.||.||||.||::.:||||||.:..|||.:..:.:|||..|::|:||:|.:||.::.||
Mouse  1023 IDKENEMLITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMG 1087

  Fly  1078 HNADVN-DNTPVDLEVYRSW---TSGQLPFFGLDHINKSRKRSSLNFSEKAIKIYN 1129
            .:..:| |...|:|:.:...   .|...|:.||||.||:.|||...:.||||||:|
Mouse  1088 RHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	518/1043 (50%)
Usp7	XP_006522201.1	Peptidase_C19	96..1141	CDD:470612	524/1053 (50%)