DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp7 and bath-36

DIOPT Version :9

Sequence 1:	NP_572779.2	Gene:	Usp7 / 32169	FlyBaseID:	FBgn0030366	Length:	1129	Species:	Drosophila melanogaster
Sequence 2:	NP_506750.1	Gene:	bath-36 / 190718	WormBaseID:	WBGene00013569	Length:	320	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	61/272 - (22%)
Similarity:	105/272 - (38%)	Gaps:	59/272 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 FTVENVVQLKSQRLSPPVYVRMLPWRIMVIP-------NDRALGFFLQCNGENDSPTWSCNA--- 160
            |.::|...|.......||.:..:.|.:....       |.:.||..|:||.|..|..|||:|
Worm    12 FEIQNFSGLAKATEHKPVQIGHVEWILGAFTSTSDATNNAKHLGIHLKCNEELRSNLWSCDASIR 76

  Fly   161 IAELRLKCHKPDAQPFTRARIKHLFYSKENDYG----YSNFITWQELKDSEKSYVHNNSITLEVH 221
            .:.|||..::.| ..|:..     |..|.:|..    .:||..|:|....:..:|.:....|||.
Worm    77 FSLLRLNSNEDD-DAFSME-----FQQKFDDLNKIVVVNNFKNWEEAICYDNRFVLDKHAVLEVQ 135

  Fly   222 VVADAPHGV------LWDS-KKHTGYVGLKNQGATCYM--------NSLLQTLYFTNSLRLSVYR 271
            :..:...|:      .:|. |:|...|.|..:|...::        :...|.::::|....:...
Worm   136 ITVNKIAGIHERIIETFDQPKEHLTDVVLVLEGKHVHVGKQVLATSSQFFQKMFYSNFAEKTQAE 200

  Fly   272 IPTEADDSSKSVGLSL-------------QRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDV 323
            |  :.||.:.|..:.|             ..|.|.|:..||....:.|.|:      ::|:..|.
Worm   201 I--KIDDVTHSEFIDLLNVIYPTHMLINSSNVSHLLKLSDRFAVPRVLEKA------ETFLILDQ 257

  Fly   324 QEFLRVLLDKLE 335
            :..   |:|||:
Worm   258 KTH---LIDKLK 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	34/136 (25%)
		COG5077	101..1119	CDD:227409	61/272 (22%)
		peptidase_C19C	239..549	CDD:239124	23/118 (19%)
		USP7_ICP0_bdg	647..886	CDD:289221
		USP7_C2	897..1113	CDD:291217
bath-36	NP_506750.1	MATH	8..137	CDD:295307	34/130 (26%)
		BTB	156..254	CDD:279045	20/105 (19%)
		BTB	161..254	CDD:197585	18/100 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910