Protein Alignment Usp7 and pqn-87

DIOPT Version :9

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_001254335.1
• Gene: pqn-87 / 174861
• WormBaseID: WBGene00004167
• Length: 1485
• Species: Caenorhabditis elegans
• Alignment Length: 1174
• Identity: 250/1174 - (21%)
• Similarity: 402/1174 - (34%)
• Gaps: 362/1174 - (30%)

  Fly    37 PPQLPKFKNLIQPQ-----------LHAVGAVTQLPSENGNMPPQQLLADSSSTSFGDGEAMGID 90
            ||.|....|..|||           ....|.|.:...:|.|..     |.||:.:.|......:|
 Worm   108 PPSLNSSTNTTQPQQAGQTTQKARAASTTGVVGEGKKQNSNAN-----ASSSNAAAGATNGKAVD 167

  Fly    91 DESKEDQFRSETTFSFTVENVVQLKSQRLSPPVYVRMLPWRIMVIP--------NDRALGFFLQC 147
            ..|..|:   .......:....||:....|||..:..:.|:|||:|        ..:.:||||||
 Worm   168 GPSWNDE---NCKLRLVINRFSQLEETMCSPPKSIEGVSWKIMVMPKQHMVQKKQQKCMGFFLQC 229

  Fly   148 NGEND-SPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDSEKSYV 211
            ..|.. |..||.:|||::|:..:||:...|.| |..|.:.|||||:|||.|:||.::.|..:.|:
 Worm   230 APERAYSDQWSVHAIADMRMISYKPNVPHFAR-RTTHTYTSKENDWGYSCFMTWADIIDEAQGYI 293

  Fly   212 HNNSITLEVHVVADAPHGVL-----------W------DSKKHTGYVGLK-NQGA---------T 249
            .::::.||:.|.|:||..::           |      ..||:...:.|: ||.|         .
 Worm   294 RDDTVVLEIAVKAEAPKNMMTHEDFLDKINKWIVLADMQMKKNNIDLALEANQSAMKFCKGKDEE 358

  Fly   250 CYMNSLLQTLYFTNS-LRLSVYRI---PTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSF 310
            ||.....|...|.|: |..|:.||   |....|::.....||::..         .|.:|
 Worm   359 CYQRLETQRETFVNAKLFESIERIEKGPVVCTDTTHGKPTSLRQAL---------TGAQK----- 409

  Fly   311 GWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYI-------KCKNVDYNS 368
                                  .|..||       |..|   ||.:..:       |.|..|.|:
 Worm   410 ----------------------SLNGKM-------TAKG---GKKARAVVTVQQMKKKKPYDQNN 442

  Fly   369 TRYETFYDIQLNIKD--------------KKNIYESFQDYVAPETLEG----------------- 402
            |..:........:||              ||::..|.::..|.|..|.
 Worm   443 TNQQRTNTGGPTVKDLVEKRKSSKSDDALKKDLLRSKEELEADEQTESEDSPDEKALGSDEEEEI 507

  Fly   403 ---DNKYDAGVHGLQ--EASKGVIF------------TSFPPVLHLHLMR-FQYDPVTDSSIKYN 449
               |.:|:.|.:|.|  |.|...:|            |::.....|.:.. ||.:  .|..:...
 Worm   508 EFDDEEYNEGDYGSQADECSTLELFGSGHDETEDGDPTAWDDETTLRIQESFQGE--NDEDVMVC 570

  Fly   450 DRF---EFYEHINLDRYLAE--SENTLADYVLHA--VLVHSGDNHGGHYVVFINPKADGRWFKFD 507
            ||.   :|.|.:   |.:.|  :.|::.|..:.|  |:...|....|...||
 Worm   571 DRMVQTDFEEAL---RSVLEDTAGNSMFDQHMLATSVIRKFGGTEEGKDTVF------------- 619

  Fly   508 DDVVSS-----CRKQEAIEQNYGG--MDDEISFHAKCSNAYMLVYIRQSELDRVLGDITESEI-- 563
            .||..|     ....::||:.:||  .:.|.:|.|             :.|| ||...|.:..
 Worm   620 QDVYFSQTGIAAAPGDSIEKIFGGESSEGEDAFSA-------------AVLD-VLPSNTPTAATA 670

  Fly   564 -SSDLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLE-KVHPRV------ 620
             |.:|.:.::.||.|:.....| |....||....:|....::..:..|.:|. |::|.:
 Worm   671 SSEELCQLVNAEKLIKKWLDVE-GALGGYVDPDGVLARLSDQDRRELLEELNFKLNPLIVSLDHE 734

  Fly   621 FR-----------------IKQNQTV---DELVDLF---VRGFGVSRQRMRMWNLCT---AQTQK 659
            ||                 ....:||   |.|.|:|   :.|..|..|:.:..|..|   |....
 Worm   735 FRETVSCVNNCLESARTALTNSQRTVTECDRLKDIFEEKLSGGFVKDQKRQADNKKTTTSAAATS 799

  Fly   660 FSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGPLPPFNPKTESLLFLKYYDPRNKRL-NY 723
            .|....|:.|..|:  |:......|: |.....:..|.:..|...:||...|...|....|: :.
 Worm   800 GSSAKSVSNGRPTV--IAKRSMKQVV-LDSDRNEERGRVSEFLKTSESAHALIQGDGETHRMRDA 861

  Fly   724 IGCTQQPHTRRLIDLVPDVNS------KLGFEPDTELTIYDEYADKKLVNLNEPIESALF--IPQ 780
            :...::.| |::..::..:||      ::..:..:|..:..| :.||||..:...:..:.  :.:
 Worm   862 LEGFKELH-RKIQPMMSMINSNNEAFHRIFTQVTSENGVVAE-SVKKLVTQHAANQQDMMTKVTK 924

  Fly   781 DHLQGHILIFERENVDAKLDLPTVGDYFLDLVYRIEIIFSDKCNPNEPDFTLELSNRYNYDQLAN 845
            .|                              ..:|:...|:           ..|...||:...
 Worm   925 AH------------------------------EALELAAEDR-----------KKNERRYDENDK 948

  Fly   846 AVAERL--NTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQ----RLS 904
            ...|..  |...||                        .||||.:..|::..|....:    .|.
 Worm   949 RATEEFDKNLKAQK------------------------EIKDLKNSLKKAENKATKEETRATTLQ 989

  Fly   905 LSIHELDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISN 969
            :.::||:.|.  |.|        .|||.....|:      .||.||      ..:.|.|.|:...
 Worm   990 VQLNELEEKA--KVV--------RKELETLKKKS------TEERAK------TKKEKDRDLQTIR 1032

  Fly   970 HKIVAVCKDDIPLDTLLKSNESIT----------TAQGAQKTFRIEEVPAEDMQLAENEFLIPVA 1024
            .:.:.:.:.:...|...|..|.:|          .|.|.|.|...|...|.::.:.||::...:.
 Worm  1033 QQSIEIVEREKERDRARKELEDVTRQKEKFEKDKKAVGGQLTSMTERARAAEVCVMENKWTAALE 1097

  Fly  1025 HFSK 1028
            .|.|
 Worm  1098 EFKK 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	49/137 (36%)
		COG5077	101..1119	CDD:227409	232/1099 (21%)
		peptidase_C19C	239..549	CDD:239124	76/393 (19%)
		USP7_ICP0_bdg	647..886	CDD:289221	39/252 (15%)
		USP7_C2	897..1113	CDD:291217	31/146 (21%)
pqn-87	NP_001254335.1	MATH_HAUSP	174..311	CDD:239741	49/140 (35%)
		PTZ00121	<828..>1162	CDD:173412	64/363 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I4935
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000