Protein Alignment Usp7 and T05H10.1

DIOPT Version :9

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_495686.2
• Gene: T05H10.1 / 174290
• WormBaseID: WBGene00011507
• Length: 1326
• Species: Caenorhabditis elegans
• Alignment Length: 946
• Identity: 220/946 - (23%)
• Similarity: 364/946 - (38%)
• Gaps: 294/946 - (31%)

  Fly   223 VADAPHGVLWDSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVY---------RIPTEADD 278
            ||:..:.:..|...|. ||||.||..|||:|||:|:||.|...|.::|         .|..:...
 Worm    71 VANNQYAIPVDENGHR-YVGLVNQAMTCYLNSLVQSLYMTPEFRNAMYDWEYVQQPAHIKEQRKK 134

  Fly   279 SSKSVGLSLQRVFHELQFGDR-PVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTI 342
            :.:|:...||::|..||..:. .:.||.||:||||.:.:::.||||||..|::.|.||.|.|||.
 Worm   135 AEQSIPCQLQKLFLLLQTSENDSLETKDLTQSFGWTSNEAYDQHDVQELCRLMFDALEHKWKGTE 199

  Fly   343 LEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKD------KKNIYESFQDYVAPETLE 401
            .|..|..|:.|.|..::.|......|.:.:.|.|:.|.:|.      .|::.|:...:|.||.|:
 Worm   200 HEKLIQDLYRGTMEDFVACLKCGRESVKTDYFLDLPLAVKPFGAIHAYKSVEEALTAFVQPELLD 264

  Fly   402 GDNKYDA-GVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYL- 464
            |.|:|.. .....|:|.||:..|.||.:|.:.|.||.:|..|...||.||:..|.:.::|:.|:
 Worm   265 GSNQYMCENCKSKQDAHKGLRITQFPYLLTIQLKRFDFDYNTMHRIKLNDKMTFPDVLDLNDYVN 329

  Fly   465 ----------------AESENTLAD---------------------------------------- 473
                            .:|||...|
 Worm   330 KEKRSTTSSAWQQIGKNKSENEEDDMELGSPNPKRCTPGVQSPNRYQGSENVCVGQPIDHAAVDD 394

  Fly   474 ---------YVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDD 529
                     |.|.:|:||||:..||||..:|......||:.|:|..|......| ||:::||...
 Worm   395 IVKTSGDNVYELFSVMVHSGNAAGGHYFAYIKNLDQDRWYVFNDTRVDFATPLE-IEKSFGGHPS 458

  Fly   530 EISFHAKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSV 594
              .::...:|||||:| |:.:..|....|..:::...:.:..:..||:|.....||....:.:.|
 Worm   459 --GWNQSNTNAYMLMY-RRIDPKRNARFILSNQLPQHIKDSQEKWKRLEREAEDERLRKLSLIQV 520

  Fly   595 HVILEENFEE----QHKRRLFDLEKVHPRVFRIKQNQTVDELVDLFVRGFG-----VSRQRMRMW 650
            :|.:...|..    ..|::| ||.   |:.::|.::             ||     :||: |.:.
 Worm   521 YVTINYPFPSVVTLPDKKQL-DLT---PQKYQIAED-------------FGEYKTEISRE-MPIK 567

  Fly   651 NLCTAQTQKFSH-FDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGPLPPFNPKTESLLFLKYY 714
            |:       |:| |:|..|.:|....                        ||...:..|:::::.
 Worm   568 NV-------FNHAFEFFNERARAYNL------------------------PFTKNSARLIYVEHG 601

  Fly   715 DPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKL-----VNLNEP--- 771
                                  .|:.|..||...             ||||     ||..||
 Worm   602 ----------------------SLMMDFKSKADM-------------DKKLRSVFNVNHGEPGSM 631

  Fly   772 ----------IESALFIPQDHLQGHILI-FERENVDAKLDL-----------------PTVGDYF 808
                      |.|: |.|.| ::..|.| .:|.::..|...                 ..:|..|
 Worm   632 YGVHFILDVRIASS-FFPVD-IKNKITIKVQRVDIGKKTTANELIVVVDANEKMIKVKSWIGGQF 694

  Fly   809 LDLVY-----RIEI-IFSDKCNPNEPDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNY 867
            .|.::     |:.: :.|.:|     :|.:       .|...||.           :|...|..|
 Worm   695 RDDIHGVLNARVVLEVASSRC-----EFMM-------IDVSHNAT-----------EFGSLIQQY 736

  Fly   868 KETAGNAVP-YTFKGTIKDLVSYTKQSST---KRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDE 928
               .|:..| ..:.|.:..:|:...|.:|   :::.:.: |:..|.||.|.....|.|....::|
 Worm   737 ---VGHTTPTLYYDGGLNTMVTKESQEATLADRKLPFDK-SVMYHILDRKCFSTMVKVRLPSQEE 797

  Fly   929 -------KELVLYPNKNDTVKGLLEE---------AAKKISFAENSRRKLRLLKISNHKIVAVCK 977
                   |.....|...:|:..:.||         |.:.:|....:       ..::|.:||
 Worm   798 IEKAASTKNAYQGPTWAETIAIMKEEDRLWNEPRAAVEVMSTVSRT-------DTTDHALVA--- 852

  Fly   978 DDIPLDTLLKSNESITTAQGAQKTFR---IEEVPAE 1010
                 ||   .:|.|.:.:|:..:.|   ::::.|:
 Worm   853 -----DT---DDEPIPSGRGSTASMRSVSMDDIDAD 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	2/5 (40%)
		COG5077	101..1119	CDD:227409	220/946 (23%)
		peptidase_C19C	239..549	CDD:239124	120/392 (31%)
		USP7_ICP0_bdg	647..886	CDD:289221	48/282 (17%)
		USP7_C2	897..1113	CDD:291217	25/133 (19%)
T05H10.1	NP_495686.2	peptidase_C19C	86..477	CDD:239124	120/395 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D387934at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820