Protein Alignment Usp7 and usp40

DIOPT Version :9

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_002932051.3
• Gene: usp40 / 100486255
• XenbaseID: XB-GENE-980927
• Length: 1226
• Species: Xenopus tropicalis
• Alignment Length: 984
• Identity: 222/984 - (22%)
• Similarity: 368/984 - (37%)
• Gaps: 244/984 - (24%)

  Fly   186 YSKENDYGYSNFITWQELKDSEKSYVHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQGATC 250
            :.::.|:   :|:.....|:.:||:..::.        ...|.|       .|...||:|||.||
 Frog     6 FEEDEDF---SFLLSSPNKNGKKSHPRDSK--------TPEPRG-------DTRLSGLRNQGGTC 52

  Fly   251 YMNSLLQTLYFTNSLRLSVYRI-PTE---------ADDSSKSVGLSLQRVFHELQFGD-RPVGTK 304
            |:|||||||:||...|.:::.: |.|         .|...:.:.|.|||:|.:|...| :.:.|.
 Frog    53 YLNSLLQTLFFTPEFREALFALGPKELGSLEEKDTPDSRVRIIPLQLQRLFAQLLLLDQQALSTT 117

  Fly   305 KLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNST 369
            .||:||||.:.:...||||||..|:|...|||.::||.....|..|:.|.:.:.|:||...|.|.
 Frog   118 DLTESFGWNSSEETSQHDVQELNRILFSALESSLEGTSGHDLIKRLYHGTIVNCIQCKECGYISE 182

  Fly   370 RYETFYDIQLNIKDKKNIYESF-QDYVAPETLEGDNKYDAG-VHGLQEASKGVIFTSFPPVLHLH 432
            |.|.|.|:.:.:|...::..|. ..|:..|..:|||.|..| ...|..|:|.......||.|.|.
 Frog   183 RQEDFLDLTVAVKGVGSLENSLCSMYLEEEHFDGDNLYRCGSCAKLVPATKSAKLGKLPPFLTLS 247

  Fly   433 LMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLAES--ENTLADYVLHAVLVHSGDNHGGHYVVFI 495
            |:||.:|.|.....|...|:.|...:.:..:..:.  |:::..|.|.:|::|.|..:||||..:|
 Frog   248 LLRFNFDFVKCERYKETSRYTFPTRLIIRPFCEQHNLEDSVYAYELFSVIIHKGGCYGGHYHAYI 312

  Fly   496 NPKAD-GRWFKFDDDVVSSCRKQEAIEQNYGGMDDEISFHAKCSNAYMLVYIRQSELDRVLGDIT 559
            ....: |.|      .:....|:.|..|......|       |....:...|.::..|::   :.
 Frog   313 QDVDELGHW------GLKEVAKKTASAQESESKQD-------CPIVALASIIAEAGADQM---VA 361

  Fly   560 ESEISSDLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLEKVHPRVFRIK 624
            ..::...|:|.:...  .....||:.|      ::|..|:.                ||.||::.
 Frog   362 VDQLGQKLLEYMGTS--WNKTYRKQHG------AMHKFLQS----------------HPSVFQMS 402

  Fly   625 QNQTVDELVDLFVRGFGVSRQRMRMW--NLCTAQTQKFSH-FDFVAEGSRTI------EQISTSQ 680
            .:.::..|........|...:..|..  ....|.::...| |||.......|      :|....:
 Frog   403 ADGSLVGLAHSVPDTVGSDSESSRPGTPEKSQAPSRSAGHWFDFNDSKVEPIRETDIEKQFQGKE 467

  Fly   681 KPWVIWLQLAWTDVPGPLPPFNP----------------------KTESLLFL----------KY 713
            ..::::.:....:.| |....||                      :|||.|.:          .:
 Frog   468 SAYMLFYRKCEMNRP-PEAKGNPRFGVPEHILNDMDQENIELQTKRTESALQINCMDLCLHLSSH 531

  Fly   714 YDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNEPIESALFI 778
            |...|      |.....|.|.        ||||....|...|:.|.   |:|         |..:
 Frog   532 YQYEN------GALHPAHPRN--------NSKLAIAIDRRRTVEDL---KQL---------AFQV 570

  Fly   779 PQDHLQGHILIFER---------EN-VDAKLDLPTVG-----DYFLDLVYRIEIIFSDK-----C 823
            ..:.|:|.:|...|         :| :|||:||.|.|     |.|         ::..|     .
 Frog   571 LDESLEGQVLSIARVLPAGLHIFQNLIDAKMDLVTAGITDGTDIF---------VWDGKQVGGVM 626

  Fly   824 NPNEPDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINN-YKETAG--------------N 873
            ..:..:||..|..........|:.|| .:...:......|:.: .||.||              |
 Frog   627 IQSGAEFTPVLLTILRPVLQTNSSAE-FSESQRAFPSCACLKDIQKELAGPTCEESVLCFPSSEN 690

  Fly   874 AVPYTF------KGTIKDLVSYTKQSSTKRIFYQRLSLSIH-------ELDNKKQFKCV--WVSS 923
            :..::|      ..::|:|  ..:..|:..:|..|....::       ..|.|:.|..|  |...
 Frog   691 SEQWSFYSADDSNKSLKEL--GLRDGSSILLFDTRSDGDVYLASERHLSKDAKQNFLMVQDWCRQ 753

  Fly   924 DLKDEKE---LVLYPN---KNDTVKG-----LLEEAAKKISFAENSRRKLRLL------------ 965
              :||||   :::.||   ::..||.     |.||.:|..:......||.:||
 Frog   754 --QDEKETVKIIITPNTTIQDIHVKAVELLQLQEECSKNDTCLRPLHRKEKLLPPVPESLTVQEA 816

  Fly   966 KISNHKIVAVCKDDIPLDT--LLKSNESITTAQGAQKTFRIEEVPAEDMQLAENEFLIPVAHFSK 1028
            ::.|...:.:||...|..:  .|.........:|:::...:||.             :.|....:
 Frog   817 ELKNGCTLGLCKGKAPSPSQIFLYFISGTDLQEGSEQEIILEET-------------LTVRQSLE 868

  Fly  1029 ELYNSFGIP 1037
            .:.|..|:|
 Frog   869 RMLNKAGLP 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	MATH_HAUSP	100..229	CDD:239741	6/42 (14%)
		COG5077	101..1119	CDD:227409	222/984 (23%)
		peptidase_C19C	239..549	CDD:239124	103/325 (32%)
		USP7_ICP0_bdg	647..886	CDD:289221	60/320 (19%)
		USP7_C2	897..1113	CDD:291217	35/175 (20%)
usp40	XP_002932051.3	UBP12	<5..>69	CDD:227847	25/80 (31%)
		Peptidase_C19	41..321	CDD:351799	96/279 (34%)
		UBP12	<439..477	CDD:227847	6/37 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D77113at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010