Protein Alignment Usp7 and usp48

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_001411018.2
• Gene: usp48 / 100332674
• ZFINID: ZDB-GENE-050522-197
• Length: 1047
• Species: Danio rerio
• Alignment Length: 1053
• Identity: 235/1053 - (22%)
• Similarity: 388/1053 - (36%)
• Gaps: 364/1053 - (34%)

  Fly   199 TWQELKDSEKSYVHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQGATCYMNSLLQTLYFTN 263
            :|  |.:.:::..||          .|.|:....|  |:| :|||.|.|||||:|:.||..:...
Zfish    62 SW--LGEIDENTFHN----------IDDPNSERRD--KNT-FVGLTNLGATCYVNTFLQVWFHNL 111

  Fly   264 SLRLSVYRIP--------TEADDSSKSVGLSLQRVFHELQFGDR----PVGTKKLTKSFGWETLD 316
            .||.::||..        |::|...:::...||.:|..||..:|    |.|   |.|:.|   ||
Zfish   112 ELRRALYRFQNSRAEGHNTDSDYEPRTICEHLQYLFALLQNSNRRYIDPSG---LVKALG---LD 170

  Fly   317 SFMQHDVQEFLRVLLDKLE---SKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQ 378
            :..|.|.|||.::.|..||   ||.|...|:..|...|.|:.|....|......|.....||:::
Zfish   171 TGQQQDAQEFSKLFLSLLEDTLSKQKDPNLQNVIQQQFCGQFSYVTVCNKCGRESPLPSRFYELE 235

  Fly   379 LNIKDKKNIYESFQDYVAPETLEGDNKYDA-GVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVT 442
            |||:..||:.|...:::..|.|:|||:|.. .....|.|::.:...|.|..|:..||||.:|..:
Zfish   236 LNIQGHKNLTECVTEFLKEEKLDGDNRYYCESCQSKQNATRRIKLQSLPRTLNFQLMRFVFDRQS 300

  Fly   443 DSSIKYNDRFEFYEHINLDRYLAESENTLADYVLHAVLVHSG-DNHGGHYVVFINPKADGRWFKF 506
            ....|.|....|.|.::::.:| |.......|.|.|||:|.| ..:.|||:..:.......|:||
Zfish   301 GHKKKLNTFISFPEVLDMEPFL-EGREEKCTYELSAVLIHRGVSAYSGHYIAHVRDAHTNDWYKF 364

  Fly   507 DDDVVSSCRKQEAIEQNYG-----GMDDEISFHAK-------------CS-NAYMLVYIRQSELD 552
            :|         |.||:..|     |::::|:..||             || |||||||.:|:|
Zfish   365 ND---------EEIEKMEGKKLQLGIEEDIAETAKSQTRKPKCSKGYHCSRNAYMLVYKQQTE-- 418

  Fly   553 RVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLEKVH 617
                :|.::|.|.|:  ...|:|.:|...||                  |||... .:.|:.|
Zfish   419 ----EINQTESSVDV--PAFLQKLVEQDNRK------------------FEEWCS-EMSDMRK-- 456

  Fly   618 PRVFRIKQNQTVDELVDLFVRGFGVSRQRMRMWNLCTA---QTQKFSHFDFV---AEGSRTIEQI 676
                     |:||       :|.....:...::.|..|   |:.:|...:::   .:.|..|::|
Zfish   457 ---------QSVD-------KGKAKHEEVKELYELLPAEDGQSYEFVPLEWLKKWLDDSTAIKEI 505

  Fly   677 STSQKPWVIWLQLAWTDVPGPLPP--------FNPKTESLLFLKY-YDPR--------------- 717
            ..||          :....|.|.|        .:.|...|||.:| ..||
Zfish   506 DNSQ----------FLCTHGKLHPDKIGEAKRISLKAADLLFSRYGGGPRLDRSSLCRDCVTQRC 560

  Fly   718 -----NKRLN---------------------YIGCTQQPHTRRL-IDLVPD-------VNSKL-- 746
                 ..:||                     :||.......|:| :|.:.:       .|||:
Zfish   561 RVIRLKNQLNEDYREVTNLAKSALKSEESGFWIGKASLRSWRQLALDQLEEDEEETKHNNSKING 625

  Fly   747 ----------GFEPDTE--------------------LTIYDEYADKKLVNLNEPIESALFIPQ- 780
                      |.:.|:|                    |:|.:.  |::||:.....:..::.|:
Zfish   626 EKSSPGTKADGVKGDSEDGDGEEMKNFNEDILCYHGGLSILEN--DRRLVSAEVWNKLRMYFPKA 688

  Fly   781 -DHLQGH-----ILIFERE--------------------NVDAKLDLPTVGDY--FLDLVYRIEI 817
             :..|.|     .:..|||                    |:..:.:.||:..:  ..|::|.:.:
Zfish   689 PEFTQDHDPCQQCMRLEREGKENEALNRMMANEQKSSLLNLFQEKNRPTLQKWPQDTDILYIVPL 753

  Fly   818 IFSD----------KCNPNEPDFTLELSN-------------RYNYDQLANAVAERLNTDPQKLQ 859
            .|.:          |.||        :||             .:.||.:       |..|.|.:.
Zfish   754 YFVEEWKKFIRRPAKGNP--------VSNVGNSILLCPHGGFMFTYDSM-------LQGDAQHIA 803

  Fly   860 FF-------------------MC-INNYKETAGNAVPYTF--------KGTI----KDLVSYTKQ 892
            ..                   :| |::..:..||....|.        :|.|    :|:..||:.
Zfish   804 LLWPAEWEVISKMFLVDQVISICRIHDKTQDNGNVQYQTHPDLCRECREGFIFQQQRDMREYTQA 868

  Fly   893 SSTKRIFYQRLSLSIHELDNKKQFK-----CVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKI 952
            :    ::.:::      :|.|:..|     .....||::||||......:.|......|..||
Zfish   869 T----VYVRKV------IDKKRMIKESAPEFSVSGSDVEDEKEEPKLDGEKDPDFSQTEGGAK-- 921

  Fly   953 SFAENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAED-MQLAE 1016
                  |:||              .|.:.|.|.:.:.   |:..|.:::.|..::..|. :.::.
Zfish   922 ------RQKL--------------NDTVSLPTAVVTT---TSKSGIRRSTRHRKLRGEKALIVSA 963

  Fly  1017 NEFL----IPVAH 1025
            |:.|    |.:.|
Zfish   964 NQTLKDLKIQIMH 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	235/1053 (22%)
usp48	NP_001411018.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	609..647		6/37 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	887..928		13/62 (21%)