Protein Alignment Usp7 and usp7

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_012826374.1
• Gene: usp7 / 100124302
• XenbaseID: XB-GENE-946612
• Length: 1104
• Species: Xenopus tropicalis
• Alignment Length: 1135
• Identity: 549/1135 - (48%)
• Similarity: 761/1135 - (67%)
• Gaps: 68/1135 - (5%)

  Fly    28 QQTQQQRNSPPQLPKFKNLIQPQLHAVGA-----VTQLPSENGNMPPQQLLADSSSTSFGDGEAM 87
            ||.|||:....||.:.:::   ::.|...     :|..|..|||:    .:||..:.:..|.|
 Frog     5 QQQQQQKPGEQQLSEPEDM---EMEAGDTDDPPRITPNPVINGNV----AMADGHNNTEEDME-- 60

  Fly    88 GIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVYVRMLPWRIMVI-------PNDRALGFFL 145
              ||.|    :|||.||.||||...:|....||||.:||.|||:|||:       |:.:::||||
 Frog    61 --DDTS----WRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFL 119

  Fly   146 QCNGENDSPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDSEKSY 210
            |||.|:||.:|||:|.|.|::..:|.:.:.|:| ||.|||:.||||:|:|||:.|.|:.|.||.:
 Frog   120 QCNAESDSTSWSCHAQAVLKIINYKDEEKFFSR-RISHLFFHKENDWGFSNFMAWSEVTDPEKGF 183

  Fly   211 VHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTE 275
            :.::.:|.||:|.|||||||.||||||||||||||||||||||||||||:|||.||.:||.:|||
 Frog   184 IEDDKVTFEVYVQADAPHGVSWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTE 248

  Fly   276 ADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKG 340
            .|||||||.|:|||||:|||..|:||||||||||||||||||||||||||..|||||.:|:||||
 Frog   249 GDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKG 313

  Fly   341 TILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNK 405
            |.:|||||.||.|||.|||:||:|||.|.|.|.:|||||:||.||||:|||.||||.|.|:||||
 Frog   314 TCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKGKKNIFESFIDYVAVEQLDGDNK 378

  Fly   406 YDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLAESEN- 469
            ||||.||||||.|||.|.:|||||||.||||.|||.||.:||.||||||.|.:.||.:|.:.::
 Frog   379 YDAGEHGLQEAEKGVKFLTFPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKPDSK 443

  Fly   470 TLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDDEISFH 534
            ..|:|:||||||||||||||||||::|||.:|:|.||||||||.|.|:||||.||||.||::|..
 Frog   444 DPANYILHAVLVHSGDNHGGHYVVYLNPKGEGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVR 508

  Fly   535 AKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSVHVILE 599
             .|:|||||||||:|:|..||..:|:.:|...|||||..|||||..:||||.||:.|:.|.::.|
 Frog   509 -HCTNAYMLVYIRESKLSEVLQAVTDQDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVTE 572

  Fly   600 ENFEEQHKRRLFDLEKVHPRVFRIKQNQTVDELVDLFVRGFGVSRQRMRMWNLCTAQ--TQKFSH 662
            :.|.......::|.|||...||::.:|.|:.|.|....:..|..:.::|:|.:....  |::.:.
 Frog   573 DQFCGHQGNDMYDEEKVKYTVFKVLKNSTLAEFVQNLSQTMGFPQDQIRLWPMQARSNGTKRPAM 637

  Fly   663 FDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVP---GPLPPFNP--KTESLLFLKYYDPRNKRLN 722
            .|:.|:.|:|:.::|.::.||.|:|:....::.   ..||.|:.  |.:.:||||.|||:::.||
 Frog   638 LDYEADCSKTMIELSDNENPWTIFLETVDPEMAASGATLPKFDKDRKYDVMLFLKMYDPKSRSLN 702

  Fly   723 YIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNEPI-------ESALFIPQ 780
            |.|....|.:.::.||:|.:..:.||...|.|.:|:|...    ||.|.|       :.||   .
 Frog   703 YCGHIYTPISCKIRDLLPVMCERAGFPQGTNLILYEEVKP----NLTERIQDYDVSLDKAL---D 760

  Fly   781 DHLQGHILIFERENVD-AKLDLPTVGDYFLDLVYRIEIIFSDKCNPNEPDFTLELSNRYNYDQLA 844
            :.:.|.|::|::::.: ...:|||..:||.||.:|:::||.||..||:|.|.:.||||.||..:|
 Frog   761 ELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYSHVA 825

  Fly   845 NAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLSIHE 909
            ..||:||||||..||||.. ..|::..||.:.:.::||::||:.:.|....|:::||:|.:.|.:
 Frog   826 KTVAQRLNTDPMLLQFFKS-QGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITD 889

  Fly   910 LDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVA 974
            .:|::.|||||::|..::| |:.|||:|:..|:.||||..:.:..:|....|||||:|.::||:.
 Frog   890 FENRRSFKCVWLNSQFREE-EVTLYPDKHGCVRDLLEECKRAVELSEKGSGKLRLLEIVSYKIIG 953

  Fly   975 VCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQL-AENEFLIPVAHFSKELYNSFGIPF 1038
            |.::|..|:.|         :....:||||||:|.:.::: .|||.||.||||.||::.:|||||
 Frog   954 VHQEDELLECL---------SPATSRTFRIEEIPLDQVEIDKENEMLITVAHFHKEVFGTFGIPF 1009

  Fly  1039 LTKARQGEPYGALKQRIQRRLNVQDKEWENYKFCVISMGHNADVNDN----TPVDLEVYRSWTSG 1099
            |.:.:||||:..:.:|||..|::|:||:|.:||.::.||.:..:|:.    :..|.|......|.
 Frog  1010 LLRIQQGEPFREVMKRIQSMLDIQEKEFEKFKFAIVMMGRHQYINEEDYEVSLKDFEPQPGNMSH 1074

  Fly  1100 QLPFFGLDHINKSRKRSSLNFSEKAIKIYN 1129
            ..|:.||||.||:.|||...:.||||||:|
 Frog  1075 PRPWLGLDHFNKAPKRSRYTYLEKAIKIHN 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	520/1045 (50%)
usp7	XP_012826374.1	Peptidase_C19	22..1102	CDD:470612	539/1114 (48%)