Protein Alignment Usp7 and usp47

DIOPT Version :10

• Sequence 1: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_031755561.1
• Gene: usp47 / 100036690
• XenbaseID: XB-GENE-5760041
• Length: 1374
• Species: Xenopus tropicalis
• Alignment Length: 1243
• Identity: 287/1243 - (23%)
• Similarity: 465/1243 - (37%)
• Gaps: 416/1243 - (33%)

  Fly    60 LPSENGNMPPQQLLADSSSTSFGDGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVY 124
            |..:||..|  ||.:|.|.|:    ::.|:||.::|                     :.:.|
 Frog   128 LTDKNGEQP--QLTSDESGTA----DSSGLDDSTQE---------------------KFIGP--- 162

  Fly   125 VRMLPWRIMVIPNDRALGFFLQCNGENDSPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKE 189
                      :|.:.::.    |..:                                   |..:
 Frog   163 ----------LPREESVA----CTSD-----------------------------------YVSQ 178

  Fly   190 NDYGYSNFITWQELKDSEKSYVHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQGATCYMNS 254
            | |.||:.:                                   ||..||||||.||..|||:||
 Frog   179 N-YSYSSLL-----------------------------------SKSDTGYVGLVNQAMTCYLNS 207

  Fly   255 LLQTLYFTNSLRLSVYRIPTE--ADDSSKSVGLSLQRVFHELQFG-DRPVGTKKLTKSFGWETLD 316
            |||||:.|...|.::|:...|  .:|...|:...|||:|..||.. .|.:.|..:|:||||::.:
 Frog   208 LLQTLFMTPEFRNALYKWEFEESEEDPVSSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE 272

  Fly   317 SFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNI 381
            ::.||||||..||:.|.||.|.|.|.....|..|::||:..|:||....|.|.|.:||.||.|.|
 Frog   273 AWQQHDVQELCRVMFDALEQKWKQTEQADLINQLYQGKLKDYVKCLECGYESWRIDTFLDIPLVI 337

  Fly   382 KD------KKNIYESFQDYVAPETLEGDNKY---------DAGVHGLQEASKGVIFTSFPPVLHL 431
            :.      ..::.|:.|.::.||||:|.|:|         |        |.||:.|..||.:|.|
 Frog   338 RPFGSNTAFGSMEEALQAFIQPETLDGPNQYFCERCKRKCD--------ARKGLKFLHFPYLLTL 394

  Fly   432 HLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYL-----------------AESE----------- 468
            .|.||.:|..:...||.|||..|.:.:::..::                 ||:|
 Frog   395 QLKRFDFDYTSMHRIKLNDRMTFPDELDMSPFIDVEDEKSPQTDSCTDSGAENEGSCHSDQMSND 459

  Fly   469 -----------------------------NTLADYVLHAVLVHSGDNHGGHYVVFINPKADGRWF 504
                                         |:|  |.|.:|:||||...||||...|...|||:|:
 Frog   460 FSTDDAVDEGICLETNSNIEKLNKSVSEKNSL--YELFSVMVHSGSAAGGHYYACIKSFADGQWY 522

  Fly   505 KFDDDVVSSCRKQEAIEQNYGGMDDEISFH----AKCSNAYMLVY-----IRQSELDRVLGDITE 560
            .|:|..||.. .||.|::.|||......::    |..:|||||:|     .|.::....:
 Frog   523 SFNDQHVSRI-TQEDIKKTYGGSTGNRGYYSSAFASSTNAYMLMYRLKNPARNAKFPEAI----- 581

  Fly   561 SEISSDLVERLDL-----EKRIEMARRKERGEANT-------YVSVHVILEENFEEQHK------ 607
                 :..|.:.|     :::.|..:|:...|.||       ...|..|:.|:..|.||
 Frog   582 -----EFPEHIKLLVQKEQEQEEQEKRQREIERNTCKLKLFCMHPVKQIMMESKLEVHKDKTMKE 641

  Fly   608 -----RRLFDLEKVHP----RVFRIKQNQTVDELVDLFVRGFGVSRQRMRMWNLCTAQTQKFSHF 663
                 .:|.|||.|..    |:.:      .||..|...|.:.....|...:.|...::...  |
 Frog   642 AVEIAHKLMDLEGVISLDCCRLVK------YDEFHDYLERSYEDEEDRTMGYLLGGVKSSYM--F 698

  Fly   664 DFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGPLPPFNPKTESLLFLKYYDPRNKRLNYIGCTQ 728
            |.:.|..|. :|:..|.||..:.:::...|:         |||::.     .|.:.|. |:..|
 Frog   699 DLLLETKRP-DQVFQSYKPGEVMVKVYVVDL---------KTETVA-----PPVSVRA-YLSQT- 746

  Fly   729 QPHTRRLIDLVPDVNSKLGFEPDTELTIYDE-YADKKLVNL-NEPIESALFIPQDHLQGHILIFE 791
                  :|:....::..:...|||...:.:. |.|.:|:|: |:.:::         :|    |.
 Frog   747 ------IIEFKQLISKSVDLLPDTMRVVLERCYNDLRLLNVANKTLKA---------EG----FF 792

  Fly   792 REN---VDAKLDLPTVGDYFLDLVYRIEIIFSDK-----CNPNEPDFTLELSNRYNYDQLANAVA 848
            |.|   |::...|    ||        :::|:|.     .:.:.....|.:|...:..|.|.:|.
 Frog   793 RSNKVFVESSDSL----DY--------QLVFTDSHLWKLLDRHANTIRLYVSLPEHTPQTARSVG 845

  Fly   849 ERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLSIHE---- 909
            .:...|          :|..|...:.|    ||.:|.:.:..::|:.|   .:.|||..|:
 Frog   846 PKGGGD----------SNLSEDYCSRV----KGNVKSVDAILEESTEK---LKSLSLQQHQDGGN 893

  Fly   910 LDNKKQFKCVWVSSDLK--------------DEKEL---VL--YPNKNDTVKGLLEEAAKKISFA 955
            .|:.|..:    .||.:              |.:||   :|  .|..|      .:...:..|..
 Frog   894 GDSSKSTE----GSDFENIDSPLNEADSGSADNRELENRILPADPENN------FQPEERSDSDV 948

  Fly   956 ENSRRKLRL---LKISNHKIVAVCKDD---IPLDTLLKSNESITTAQ------GAQKTF-RIEEV 1007
            .|.|....:   :..|:|....:|..|   |||...|.|: |||:::      |.::|: ..||.
 Frog   949 NNDRSTSSVDSDILSSSHSSDTLCNADSAPIPLANGLDSH-SITSSRRSKANDGKKETWDTAEED 1012

  Fly  1008 PAEDMQLAEN-------EFLIPVAHFSKELYNSFGIPFLTKARQGEPYGALKQRIQRRLNVQDKE 1065
            ...|.:..|:       :::    :|..|       |...:...||....|...:.:|:.:...:
 Frog  1013 SGTDSEYDESGKSRGEAQYM----YFKAE-------PHAGEGCLGEGNKCLLVSVDKRITLAAFK 1066

  Fly  1066 WENYKFCVISMGHNADVNDNTPVDLEVYRSWTSGQ----------LPFFGLDHINKSRKRSSLNF 1120
            .:...|..:|..           ..:|:|.:.|.|          |..|..|:....|...:|..
 Frog  1067 QQLESFVGVSSS-----------QFKVFRVYASNQEFESVRLNETLSSFSDDNKITIRLGRALKK 1120

  Fly  1121 SEKAIKIY 1128
            .|..:||:
 Frog  1121 GEYRVKIF 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	270/1191 (23%)
usp47	XP_031755561.1	peptidase_C19C	192..571	CDD:239124	132/389 (34%)
		USP47_C	1124..1362	CDD:466158	2/5 (40%)