DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and ERB1

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_013764.1 Gene:ERB1 / 855068 SGDID:S000004652 Length:807 Species:Saccharomyces cerevisiae


Alignment Length:406 Identity:78/406 - (19%)
Similarity:124/406 - (30%) Gaps:163/406 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   151 PSIPKPKWHAPW--KLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLT-- 211
            |.:|.||...|:  :.|.:.:||.|.||.::::|...|.|||:.|..:::|::.:|:.....|  
Yeast   414 PELPSPKDLRPFPIRCSTIYAGHKGKVRTLSIDPSGLWLATGSDDGTVRVWEILTGREVYRTTLI 478

  Fly   212 -------GHVSTVR----------GVAVSTK-H---PYLFSC----------------------- 232
                   .|:..:.          .|||... |   |.:|..                       
Yeast   479 DDEENPDYHIECIEWNPDANNGILAVAVGENIHLIVPPIFGYDIENNGKTKIEDGFGYDTFGTVK 543

  Fly   233 ---------------GEDRQVK----------------------CWDLEYNKVIRHYHGHLSAVY 260
                           ||:...|                      |..:...|.::....|....|
Yeast   544 KSNLEVNENGDGDEDGENESAKNAVKKQVAQWNKPSQKQLEKDICITISCKKTVKKLSWHRKGDY 608

  Fly   261 SLALHPTIDVLATSGRDST----------------------------------------ARIWDM 285
            .:.:.|      .||..|.                                        .||:|:
Yeast   609 FVTVQP------DSGNTSVLIHQVSKHLTQSPFKKSKGIIMDAKFHPFKPQLFVCSQRYVRIYDL 667

  Fly   286 RTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLW---DLAAGKSVCTLTNHKKSVRSIV 347
            ..:..|..|......::.:........:|..|.|..| ||   |||: ....||..|:|:|||:.
Yeast   668 SQQILVKKLLPGARWLSKIDIHPRGDNLIASSFDKRV-LWHDLDLAS-TPYKTLRYHEKAVRSVN 730

  Fly   348 LHPSLYMFASASPDNI----------KQWRCPEGKFVQNISGHTSIVNCMAANSEGV-------- 394
            .|..|.:|:||:.|..          ...:.|....::.::||..|      ||.||        
Yeast   731 FHKKLPLFSSAADDGTIHVFHATVYDDMMKNPMIVPLKKLTGHKVI------NSLGVLDAIWHPR 789

  Fly   395 ---LVSGGDNGTMFFW 407
               |.|.|.:.|...|
Yeast   790 EAWLFSAGADNTARLW 805

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 74/396 (19%)
WD40 164..458 CDD:238121 73/391 (19%)
WD40 repeat 177..212 CDD:293791 9/43 (21%)
WD40 repeat 218..254 CDD:293791 11/109 (10%)
WD40 repeat 259..295 CDD:293791 9/75 (12%)
WD40 repeat 302..337 CDD:293791 10/37 (27%)
WD40 repeat 343..378 CDD:293791 10/44 (23%)
WD40 repeat 386..426 CDD:293791 9/33 (27%)
WD40 repeat 433..457 CDD:293791
ERB1NP_013764.1 BOP1NT 165..426 CDD:400453 5/11 (45%)
WD40 429..805 CDD:421866 72/389 (19%)
WD40 repeat 441..483 CDD:293791 10/41 (24%)
WD40 repeat 488..540 CDD:293791 6/51 (12%)
WD40 repeat 598..637 CDD:293791 6/44 (14%)
WD40 repeat 642..676 CDD:293791 4/33 (12%)
WD40 repeat 684..720 CDD:293791 10/37 (27%)
WD40 repeat 726..771 CDD:293791 10/44 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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