DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and DUF1

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_014554.1 Gene:DUF1 / 854066 SGDID:S000005447 Length:1116 Species:Saccharomyces cerevisiae


Alignment Length:334 Identity:62/334 - (18%)
Similarity:105/334 - (31%) Gaps:131/334 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 TSLVRASLANSNADMSANGAIASH---LQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAV 180
            :.|:..::.||:..........||   :.||...|..       ..|. .::|..|..:::||..
Yeast    83 SDLIHVNMKNSDPSAGDTFISVSHDFSIVLISVNAQL-------TTWD-KKIIGDHDDYIKCIVP 139

  Fly   181 --------------------------------EPGNEWFATGAGDRVIKIWDLASGKLKLSL--- 210
                                            |..|..|.||..||.||:|.|:||..|::.   
Yeast   140 IHYEMSNDYELEEQEGGPDNVHDGINNGIVVDEQNNFLFVTGGLDRKIKLWCLSSGPEKMATLLH 204

  Fly   211 ---------TGHVSTVRGVAV-------STKHPYLFSCGE-DRQVKCWDLEYNK-VIRHYHGHLS 257
                     ||.:.::..:..       .|..|:.|..|: :..:..:..:|.| |||..:.|.:
Yeast   205 TFDNAQSNDTGSIYSMSPIIPKYSFDDNQTSRPFDFVAGDCNGDLIFYSCKYRKEVIRIQNAHRT 269

  Fly   258 AVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTV 322
               ::.:..|:|       |||                                ::|:.|.|..:
Yeast   270 ---NIKVVRTLD-------DST--------------------------------RLISTSSDGVI 292

  Fly   323 RLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWR------CPEGKFVQNISGHT 381
            .:|||..        .|.::..::.|           |..|..|.      |.:|..:..:....
Yeast   293 NVWDLNC--------RHDQTTGALQL-----------PKKIGSWSWDSSIWCVQGTSLDKLYFGD 338

  Fly   382 SIVNCMAAN 390
            |..|.|.||
Yeast   339 SQGNVMRAN 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 54/289 (19%)
WD40 164..458 CDD:238121 53/286 (19%)
WD40 repeat 177..212 CDD:293791 16/78 (21%)
WD40 repeat 218..254 CDD:293791 9/44 (20%)
WD40 repeat 259..295 CDD:293791 5/35 (14%)
WD40 repeat 302..337 CDD:293791 6/34 (18%)
WD40 repeat 343..378 CDD:293791 6/40 (15%)
WD40 repeat 386..426 CDD:293791 3/5 (60%)
WD40 repeat 433..457 CDD:293791
DUF1NP_014554.1 WD40 10..296 CDD:421866 47/262 (18%)
WD40 repeat 165..207 CDD:293791 14/41 (34%)
WD40 repeat 218..264 CDD:293791 9/45 (20%)
WD40 repeat 271..309 CDD:293791 12/84 (14%)
WD40 repeat 337..383 CDD:293791 5/11 (45%)
WD40 repeat 392..418 CDD:293791
Ubl_WDR48 1018..1098 CDD:340561
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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