DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango4 and RACK1B_AT

DIOPT Version :9

Sequence 1:	NP_572778.1	Gene:	Tango4 / 32168	FlyBaseID:	FBgn0030365	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_175296.1	Gene:	RACK1B_AT / 841284	AraportID:	AT1G48630	Length:	326	Species:	Arabidopsis thaliana

Alignment Length:	333	Identity:	76/333 - (22%)
Similarity:	139/333 - (41%)	Gaps:	55/333 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LVTGT---HTSLVRA-SLANSNADMSANGAIASHLQLIPKKAPSIPKPKWHAPWKLS-------- 165
            ::.||   ||.:|.| :....|:|:....:....:.|                |||:
plant     6 VLKGTMCAHTDMVTAIATPVDNSDVIVTSSRDKSIIL----------------WKLTKEDKSYGV 54

  Fly   166 --RVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPY 228
              |.::||..:|:.:.:....::..:|:.|..:::||||:|:......||...|..||.||.:..
plant    55 AQRRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQ 119

  Fly   229 LFSCGEDRQVKCWDL--EYNKVIRHYHGHLSAVYSLALHPT--IDVLATSGRDSTARIWDMRTKA 289
            :.|...||.:|.|:.  |....|....||...|..:...|.  :..:.::..|.|.::|:::...
plant   120 IVSASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQNCK 184

  Fly   290 NVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYM 354
            ..:||.||:..:.:|..........:|..|..:.|||||.||.:.:| .....:.|:...|:.|.
plant   185 LRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSL-EAGSIIHSLCFSPNRYW 248

  Fly   355 FASASPDNIKQWRCPEGKFVQN-----------------ISGHTSIVNCMAAN--SEG-VLVSGG 399
            ..:|:.::|:.|.......|::                 |...|.::.|.:.|  ::| .|.||.
plant   249 LCAATENSIRIWDLESKSVVEDLKVDLKAEAEKTDGSTGIGNKTKVIYCTSLNWSADGNTLFSGY 313

  Fly   400 DNGTMFFW 407
            .:|.:..|
plant   314 TDGVIRVW 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	67/281 (24%)
		WD40	164..458	CDD:238121	65/278 (23%)
		WD40 repeat	177..212	CDD:293791	7/34 (21%)
		WD40 repeat	218..254	CDD:293791	11/37 (30%)
		WD40 repeat	259..295	CDD:293791	6/37 (16%)
		WD40 repeat	302..337	CDD:293791	10/34 (29%)
		WD40 repeat	343..378	CDD:293791	7/51 (14%)
		WD40 repeat	386..426	CDD:293791	8/25 (32%)
		WD40 repeat	433..457	CDD:293791
RACK1B_AT	NP_175296.1	WD40	6..321	CDD:238121	75/331 (23%)
		WD40 repeat	18..61	CDD:293791	9/58 (16%)
		WD40 repeat	67..103	CDD:293791	7/35 (20%)
		WD40 repeat	108..144	CDD:293791	12/35 (34%)
		WD40 repeat	153..190	CDD:293791	5/36 (14%)
		WD40 repeat	196..232	CDD:293791	11/36 (31%)
		WD40 repeat	237..279	CDD:293791	7/41 (17%)
		WD40 repeat	297..321	CDD:293791	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910