DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tango4 and TAF5

DIOPT Version :9

Sequence 1:	NP_572778.1	Gene:	Tango4 / 32168	FlyBaseID:	FBgn0030365	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_197897.3	Gene:	TAF5 / 832586	AraportID:	AT5G25150	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	415	Identity:	105/415 - (25%)
Similarity:	156/415 - (37%)	Gaps:	78/415 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQTPGDKTLAITDGSATDA---------- 90
            :::||||..         ||:.|.....||::                ||.|.|:
plant   236 LEDRLEKTG---------GLLSDSEKGQGESK----------------DGDADDSKKRSTEIGKQ 275

  Fly    91 ASGAGSLVKYNAGARPAEKTAPL--VTGTHTSLVRASLA----NSNADMSANGAIASHLQLIPKK 149
            .|....|.|..||...| |.|.|  :|.:....|:..||    :::.:.|....:.:.:||....
plant   276 GSSLKKLKKDKAGNATA-KVARLETITVSPAPRVKPELALPVMSTDVEQSILEDLRNRVQLSSVA 339

  Fly   150 APSIPKPKWHAPWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLA------SGKLKL 208
            .||:         .....::.|.| :.|.::.......|.|..|..||:||:|      ||.|:.
plant   340 MPSV---------SFYTFVNTHNG-LNCSSISHDGSLVAGGFSDSSIKVWDMAKIGQAGSGALQA 394

  Fly   209 S------------------LTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGH 255
            .                  |.||...|.....|....::.|...|..::.|..:.|..:..|.||
plant   395 ENDSSDQSIGPNGRRSYTLLLGHSGPVYSATFSPPGDFVLSSSADTTIRLWSTKLNANLVCYKGH 459

  Fly   256 LSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDS 320
            ...|:.....|.....|:...|.|||||.|.....:..:.||.:.|..|........|.|||.|.
plant   460 NYPVWDAQFSPFGHYFASCSHDRTARIWSMDRIQPLRIMAGHLSDVDCVQWHPNCNYIATGSSDK 524

  Fly   321 TVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPD-NIKQWRCPEGKFVQNISGHTSIV 384
            ||||||:..|:.|.....|:..|.|:.:.|.....||...| .|..|.....:.:..:.||.|.|
plant   525 TVRLWDVQTGECVRIFIGHRSMVLSLAMSPDGRYMASGDEDGTIMMWDLSTARCITPLMGHNSCV 589

  Fly   385 NCMAANSEG-VLVSGGDNGTMFFWD 408
            ..::.:.|| :|.||..:.|:..||
plant   590 WSLSYSGEGSLLASGSADCTVKLWD 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	74/274 (27%)
		WD40	164..458	CDD:238121	74/271 (27%)
		WD40 repeat	177..212	CDD:293791	13/58 (22%)
		WD40 repeat	218..254	CDD:293791	6/35 (17%)
		WD40 repeat	259..295	CDD:293791	10/35 (29%)
		WD40 repeat	302..337	CDD:293791	14/34 (41%)
		WD40 repeat	343..378	CDD:293791	8/35 (23%)
		WD40 repeat	386..426	CDD:293791	8/24 (33%)
		WD40 repeat	433..457	CDD:293791
TAF5	NP_197897.3	TFIID_NTD2	64..188	CDD:398277
		WD40 repeat	357..416	CDD:293791	13/58 (22%)
		WD40	414..663	CDD:238121	60/201 (30%)
		WD40 repeat	422..458	CDD:293791	6/35 (17%)
		WD40 repeat	463..499	CDD:293791	10/35 (29%)
		WD40 repeat	506..541	CDD:293791	14/34 (41%)
		WD40 repeat	547..583	CDD:293791	8/35 (23%)
		WD40 repeat	589..622	CDD:293791	9/26 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910