DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango4 and AT2G40360

DIOPT Version :9

Sequence 1:	NP_572778.1	Gene:	Tango4 / 32168	FlyBaseID:	FBgn0030365	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_181567.3	Gene:	AT2G40360 / 818629	AraportID:	AT2G40360	Length:	753	Species:	Arabidopsis thaliana

Alignment Length:	395	Identity:	79/395 - (20%)
Similarity:	137/395 - (34%)	Gaps:	131/395 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 PSIPKPKWHAPWKLSRVI--SGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGK-LKL---- 208
            |.:|..|...|:..|..:  .||.|.|..|:.:...||.|:|:.|..:::|::.:|: ||:
plant   400 PKLPSRKDLRPYPNSCYLEYKGHTGAVTSISTDSSGEWIASGSTDGSVRMWEVETGRCLKVWQFD 464

  Fly   209 -----SLTGHVSTVRGVAVSTKHPYLF---SCGEDRQ----------------------VKCW-- 241
                 .....:|.:..:||:......|   ..|.|.:                      :..|
plant   465 EAIMCVAWNPLSRLPVLAVAMGRDLFFLNTELGTDEEQEITKERLHSGNIPEPDASVAAIVTWLP 529

  Fly   242 DLEYNKV-IRHYHGHLSAVYSLALHPTIDVLAT---SG-----------RDSTARI--------- 282
            |..|..: |||:    .::.|:..|...|.|:|   ||           :..|.|:
plant   530 DELYGGIKIRHF----KSISSIDWHRKGDYLSTVMASGETRGVVLHQLSKQKTQRLPFKIRGLPV 590

  Fly   283 ----------WDMRTKANVHTL-------------TGHTNTVASVVAQATNPQIITGSHDSTVRL 324
                      :.:.|:.:|...             || ...::|:........:|.||.:..:..
plant   591 CTLFHPSLSYFFVATRKDVRVYNLLKPGEATKKLETG-LREISSMAIHPGGDNLIVGSKEGKMCW 654

  Fly   325 WDL-AAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISGHTSIVNCMA 388
            :|: .:.|...||.||.|.:.::.:|.|..:|||.|.|:.        .:|    .|..:.|.:
plant   655 FDMDLSSKPYKTLKNHPKDITNVAVHRSYPLFASCSEDST--------AYV----FHGMVYNDL- 706

  Fly   389 ANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQ-PGSMDSEAGIFAMCFDQSGSRLITAEADK 452
             |...::|                        |:: .....|:.|:....|......|.||.||.
plant   707 -NQNPLIV------------------------PLEILRGHSSKGGVLDCKFHPRQPWLFTAGADS 746

  Fly   453 TIKVY 457
            .||:|
plant   747 IIKLY 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	76/385 (20%)
		WD40	164..458	CDD:238121	75/382 (20%)
		WD40 repeat	177..212	CDD:293791	10/44 (23%)
		WD40 repeat	218..254	CDD:293791	11/63 (17%)
		WD40 repeat	259..295	CDD:293791	11/81 (14%)
		WD40 repeat	302..337	CDD:293791	7/35 (20%)
		WD40 repeat	343..378	CDD:293791	8/34 (24%)
		WD40 repeat	386..426	CDD:293791	3/40 (8%)
		WD40 repeat	433..457	CDD:293791	8/23 (35%)
AT2G40360	NP_181567.3	BOP1NT	157..412	CDD:285371	4/11 (36%)
		WD40	415..751	CDD:295369	73/378 (19%)
		WD40	417..>751	CDD:225201	73/376 (19%)
		WD40 repeat	426..463	CDD:293791	11/36 (31%)
		WD40 repeat	468..509	CDD:293791	6/40 (15%)
		WD40 repeat	545..582	CDD:293791	9/36 (25%)
		WD40 repeat	589..625	CDD:293791	2/35 (6%)
		WD40 repeat	631..671	CDD:293791	9/39 (23%)
		WD40 repeat	674..698	CDD:293791	8/35 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910