DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and Thoc6

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_077360.2 Gene:Thoc6 / 79227 RGDID:708553 Length:341 Species:Rattus norvegicus


Alignment Length:256 Identity:56/256 - (21%)
Similarity:98/256 - (38%) Gaps:61/256 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 AVEPGNEWFATGAGDRVIKIWDLA----------SGKLKLSLTGHVSTVRGVAVSTKHPYLFSCG 233
            :|.|..::.|.|.....|.|:.|:          |.|..::...|...|..:..:.:|  |.|.|
  Rat    31 SVSPCGKFLAAGNNYGQIAIFSLSAALSSEAKEESKKPMVTFHAHDGPVYSMVSTDRH--LLSAG 93

  Fly   234 EDRQVKCWDLEYNKVIRH-----------YHGHLSA--VYSLALHPTIDVLATSGRDSTARIWDM 285
             |.:||.|  .:.::::.           |...|..  :.:|.|.|..:.|..:|.|......|:
  Rat    94 -DGEVKGW--LWAEILKKGCKELWRRQPPYRTSLEVPEINALLLVPKENSLILAGGDCQLHTMDL 155

  Fly   286 RTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHP 350
            .|......|.|||:.:..:..:..:|::::|..|..||||||...|.|.|:              
  Rat   156 ETGTFTRALRGHTDYIHCLALRERSPEVLSGGEDGAVRLWDLRIAKEVQTI-------------- 206

  Fly   351 SLYMFASASPDNIKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVSGGDNGTMFFWDWRT 411
            .:|.....|..:..:|                 :.|:|.:|:.::..||...|:  |..|:
  Rat   207 EVYKHEECSRPHNGRW-----------------IGCLATDSDWMVCGGGPALTL--WHLRS 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 56/256 (22%)
WD40 164..458 CDD:238121 56/256 (22%)
WD40 repeat 177..212 CDD:293791 9/42 (21%)
WD40 repeat 218..254 CDD:293791 9/46 (20%)
WD40 repeat 259..295 CDD:293791 8/35 (23%)
WD40 repeat 302..337 CDD:293791 12/34 (35%)
WD40 repeat 343..378 CDD:293791 3/34 (9%)
WD40 repeat 386..426 CDD:293791 8/26 (31%)
WD40 repeat 433..457 CDD:293791
Thoc6NP_077360.2 WD 1 22..61 7/29 (24%)
WD40 27..285 CDD:421866 56/256 (22%)
WD40 repeat 28..74 CDD:293791 9/42 (21%)
WD 2 74..112 10/42 (24%)
WD40 repeat 79..115 CDD:293791 9/40 (23%)
WD 3 124..163 9/38 (24%)
WD40 repeat 130..165 CDD:293791 8/34 (24%)
WD 4 166..205 14/38 (37%)
WD40 repeat 171..210 CDD:293791 12/52 (23%)
WD 5 215..254 10/53 (19%)
WD40 repeat 218..260 CDD:293791 9/50 (18%)
WD 6 256..293
WD 7 295..339
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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