DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and Wdr61

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_001020546.1 Gene:Wdr61 / 66317 MGIID:1917493 Length:305 Species:Mus musculus


Alignment Length:304 Identity:69/304 - (22%)
Similarity:125/304 - (41%) Gaps:26/304 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   158 WHAPWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKL--SLTGHVSTVRGV 220
            |...|:.::              :...|...||:.|.::|:|.....:|:|  ||.||...|..|
Mouse    20 WSVAWETNK--------------KENIETVVTGSLDDLVKVWKWRDERLELQWSLEGHQLGVVSV 70

  Fly   221 AVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDM 285
            .:|...|...|...|..::.||||..|.::.........::||..|....|||........|:.:
Mouse    71 DISHTLPIAASSSLDAHIRLWDLENGKQMKSIDAGPVDAWTLAFSPDSQYLATGTHMGKVNIFGV 135

  Fly   286 RTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHP 350
            .:....::|......:.|:........:.:|:.|..:.::|:|.||.:.||..|...:||:...|
Mouse   136 ESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSP 200

  Fly   351 SLYMFASASPDN-IKQWRCPEGKFVQNISGHTS-IVNCMAANSEGVLVSGGDNGTMFFWDWRTGY 413
            ...:..:||.|. ||.:..........:|||.| ::|......:...||...:.::..||..|..
Mouse   201 DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRT 265

  Fly   414 NFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVY 457
            ....|        .|.:..::.:.::.:||::::...|:.|.||
Mouse   266 CIHTF--------FDHQDQVWGVKYNGNGSKIVSVGDDQEIHVY 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 68/301 (23%)
WD40 164..458 CDD:238121 67/298 (22%)
WD40 repeat 177..212 CDD:293791 10/36 (28%)
WD40 repeat 218..254 CDD:293791 10/35 (29%)
WD40 repeat 259..295 CDD:293791 7/35 (20%)
WD40 repeat 302..337 CDD:293791 8/34 (24%)
WD40 repeat 343..378 CDD:293791 8/35 (23%)
WD40 repeat 386..426 CDD:293791 6/39 (15%)
WD40 repeat 433..457 CDD:293791 4/23 (17%)
Wdr61NP_001020546.1 WD40 13..302 CDD:238121 69/304 (23%)
WD 1 14..57 9/50 (18%)
WD40 repeat 19..62 CDD:293791 12/55 (22%)
WD 2 62..101 13/38 (34%)
WD40 repeat 68..105 CDD:293791 10/36 (28%)
WD 3 104..143 7/38 (18%)
WD40 repeat 110..146 CDD:293791 8/35 (23%)
WD 4 146..187 8/40 (20%)
WD40 repeat 152..188 CDD:293791 9/35 (26%)
WD 5 188..227 9/38 (24%)
WD40 repeat 193..229 CDD:293791 8/35 (23%)
WD 6 230..269 9/38 (24%)
WD40 repeat 236..271 CDD:293791 7/42 (17%)
WD 7 272..305 7/30 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53955
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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