DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and NBEAL1

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:XP_006712761.1 Gene:NBEAL1 / 65065 HGNCID:20681 Length:2736 Species:Homo sapiens


Alignment Length:227 Identity:60/227 - (26%)
Similarity:90/227 - (39%) Gaps:55/227 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 IPKKAPSIPK-----------PKWHAPWKLSRVISGHLGWV---RCIAVEPGNEWFATGAGDRVI 196
            ||....:|||           |:......::.||..| ||:   |.|     :.:|.      .|
Human  2352 IPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTH-GWLPYDRNI-----SNYFT------FI 2404

  Fly   197 KIWDLASGKLKLSLTGHVSTVRGVAVSTK-----H--PYLFSCGE-DRQVKCWDLEYNKVIRHYH 253
            |...:.:.|.:.|:.|  |...|:.:::|     |  ..|||.|. |..::...|...|:|.|..
Human  2405 KDQTVTNPKTQRSING--SFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHII 2467

  Fly   254 GHLSAVYSLA-----LHPTIDVLATSGRDSTARIWDMRTKANV---------HTLTGHTNTVASV 304
            .|:..|..||     :|     |.:..||:|..||.:..:..|         ..|.||||.|.||
Human  2468 RHMDIVTCLATDYCGIH-----LISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSV 2527

  Fly   305 VAQATNPQIITGSHDSTVRLWDLAAGKSVCTL 336
            .........::||.|.||.:..:..|:.:.||
Human  2528 GISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 2559

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 54/201 (27%)
WD40 164..458 CDD:238121 54/198 (27%)
WD40 repeat 177..212 CDD:293791 6/34 (18%)
WD40 repeat 218..254 CDD:293791 12/43 (28%)
WD40 repeat 259..295 CDD:293791 11/49 (22%)
WD40 repeat 302..337 CDD:293791 10/35 (29%)
WD40 repeat 343..378 CDD:293791
WD40 repeat 386..426 CDD:293791
WD40 repeat 433..457 CDD:293791
NBEAL1XP_006712761.1 DUF4704 888..1148 CDD:292415
DUF4800 1609..1862 CDD:292675
PH_BEACH 1915..2012 CDD:275391
Beach 2034..2313 CDD:280327
WD40 <2390..2699 CDD:225201 50/188 (27%)
WD40 repeat 2435..2468 CDD:293791 10/32 (31%)
WD40 2438..2682 CDD:295369 37/127 (29%)
WD40 repeat 2474..2519 CDD:293791 11/49 (22%)
WD40 repeat 2524..2560 CDD:293791 11/36 (31%)
WD40 repeat 2572..2606 CDD:293791
WD40 repeat 2619..2654 CDD:293791
WD40 repeat 2659..2699 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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