DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tango4 and tle2b

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:XP_021329162.1 Gene:tle2b / 564019 ZFINID:ZDB-GENE-050208-677 Length:763 Species:Danio rerio


Alignment Length:380 Identity:82/380 - (21%)
Similarity:134/380 - (35%) Gaps:89/380 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 GAGSLVKYNAGARPAEKTAPLVTGTHTSLVRASLANSNADMSANG--AIASH------LQLIP-- 147
            |:.:|....:.|..|...:|:|.....|.:|.|..:|:...|.:|  |.:.|      :|.:|  
Zfish   391 GSLTLSPQISAAASAYTRSPMVAYESRSHLRPSGLSSSLPGSTSGKPAYSFHVSADGQMQPVPFP 455

  Fly   148 ---KKAPSIPKPKWHA---------------------------------PWKLSRVIS------- 169
               ...|.||:   ||                                 .|.:|:..|       
Zfish   456 PDALLGPGIPR---HARQIHTLSHGEVVCAVTISTSTRHVYTGGKGCVKVWDISQPGSKSPMAQL 517

  Fly   170 ---GHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLA--SGKLKLSLTGHVSTVRGVAVSTKHPYL 229
               ....::|...:.|.......|.....:.|||||  :.::|..||........:|:|..:...
Zfish   518 DCLNRDNYIRSCKILPDGRTLIVGGEASTLSIWDLATPTPRIKAELTSSAPACYALAISPDNKVC 582

  Fly   230 FSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTL 294
            |||..|..:..|||....::|.:.||......:.:......|.|.|.|:|.|.||:|   ....|
Zfish   583 FSCCSDGNIVVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRCWDLR---EGRQL 644

  Fly   295 TGH--TNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYM--- 354
            ..|  |:.:.|:....|...:..|...|.|.:..::           |.....:.||.|..:   
Zfish   645 QQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVS-----------KPDKYQLHLHESCVLSLK 698

  Fly   355 -------FASASPDN-IKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVSG-GD 400
                   |.|...|| :..||.|.|..:......:|:::|..:..:..:|:| ||
Zfish   699 FAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDVSPDDKYIVTGSGD 753

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 61/266 (23%)
WD40 164..458 CDD:238121 60/263 (23%)
WD40 repeat 177..212 CDD:293791 9/36 (25%)
WD40 repeat 218..254 CDD:293791 10/35 (29%)
WD40 repeat 259..295 CDD:293791 9/35 (26%)
WD40 repeat 302..337 CDD:293791 5/34 (15%)
WD40 repeat 343..378 CDD:293791 11/45 (24%)
WD40 repeat 386..426 CDD:293791 5/16 (31%)
WD40 repeat 433..457 CDD:293791
tle2bXP_021329162.1 TLE_N 1..128 CDD:309152
WD40 471..760 CDD:238121 61/297 (21%)
WD40 repeat 480..519 CDD:293791 3/38 (8%)
WD40 repeat 527..565 CDD:293791 10/37 (27%)
WD40 repeat 570..606 CDD:293791 10/35 (29%)
WD40 repeat 613..648 CDD:293791 10/37 (27%)
WD40 repeat 653..686 CDD:293791 6/43 (14%)
WD40 repeat 694..728 CDD:293791 8/33 (24%)
WD40 repeat 735..759 CDD:293791 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.