DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and strn4

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:XP_021321999.1 Gene:strn4 / 562780 ZFINID:ZDB-GENE-070501-3 Length:768 Species:Danio rerio


Alignment Length:392 Identity:89/392 - (22%)
Similarity:131/392 - (33%) Gaps:110/392 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 GEARKASGAQTPGDKTLAITDGSATDAASGAGSLVKYNAGARPAEKTAPLVTGTHTSLVRASLAN 128
            |:||...|........:.|.|      |.|.|.:   |.|     :.|.|.......|. ..|.:
Zfish   386 GQARSGEGGALGFSSDVFILD------AVGGGDM---NLG-----ELADLTVANDNDLT-IDLQD 435

  Fly   129 SNADM----SANGAIASHLQLI------PKKAP--SIPKPKWHAPWKLSRVI------------- 168
            |..:.    :....:.||...|      |.:|.  |..:......|.|::.:             
Zfish   436 SREEFKKTWNPRFTLRSHFDAIRALSFHPSQAVLLSASEDGTLKLWNLNKAMHSKKNAALDVEPI 500

  Fly   169 ---SGHLGWVRCIAV-EPGNEWFATGAGDRVIKIWDLAS-----------GKLKLSLTGHVSTVR 218
               ..|.|.|..:|: |.|...|:.|. |..|:.|.:..           |.....|:||...|.
Zfish   501 YTFRAHSGAVLSLAMGEEGESCFSGGL-DGTIRGWKIPDLNVDPYDNYDPGVESSVLSGHEDAVW 564

  Fly   219 GVAVSTKHPYLFSCGEDRQVKCWDLE--------YNK-------------------VIRHYHGHL 256
            |:|.|:....|.||..|..|:.||..        :||                   |:..:.|..
Zfish   565 GLAFSSSLQRLASCSADGTVRIWDPHNSSPCVSVFNKEKEHGTPTSVAFVNADPSQVVVSFDGGE 629

  Fly   257 SAVYSLALHPTIDVLATSGRDS-----------------------TARIWDMRTKANVHTLTGHT 298
            :.:|.|....:|.||.|..:|.                       |.|..|..|...:|::..|.
Zfish   630 TLLYDLNTEQSIMVLETQTKDGSELINRVVSHPSQPISITAHENRTIRFLDNNTGKVIHSMVAHL 694

  Fly   299 NTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKK----SVRSIVLHPSLYMFASAS 359
            :.|..:........:|:||||.:||||.|.....|..:|.|:|    ::..:..|||....|||.
Zfish   695 DAVTCLATDPKGTYLISGSHDCSVRLWMLDNRTCVQEITAHRKKHDEAIHDVAFHPSQPFIASAG 759

  Fly   360 PD 361
            .|
Zfish   760 AD 761

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 67/283 (24%)
WD40 164..458 CDD:238121 66/280 (24%)
WD40 repeat 177..212 CDD:293791 10/46 (22%)
WD40 repeat 218..254 CDD:293791 13/62 (21%)
WD40 repeat 259..295 CDD:293791 12/58 (21%)
WD40 repeat 302..337 CDD:293791 11/34 (32%)
WD40 repeat 343..378 CDD:293791 7/19 (37%)
WD40 repeat 386..426 CDD:293791
WD40 repeat 433..457 CDD:293791
strn4XP_021321999.1 Striatin 65..191 CDD:311929
WD40 446..767 CDD:238121 73/317 (23%)
WD40 repeat 459..505 CDD:293791 5/45 (11%)
WD40 repeat 511..558 CDD:293791 10/47 (21%)
WD40 repeat 563..600 CDD:293791 11/36 (31%)
WD40 repeat 609..645 CDD:293791 6/35 (17%)
WD40 repeat 655..691 CDD:293791 5/35 (14%)
WD40 repeat 697..737 CDD:293791 14/39 (36%)
WD40 repeat 743..767 CDD:293791 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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