Protein Alignment Tango4 and plrg1

DIOPT Version :10

• Sequence 1: NP_572778.1
• Gene: Tango4 / 32168
• FlyBaseID: FBgn0030365
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_001032331.1
• Gene: plrg1 / 394977
• XenbaseID: XB-GENE-964754
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 309/516 - (59%)
• Similarity: 368/516 - (71%)
• Gaps: 43/516 - (8%)

  Fly     3 MEDVQKHSVHTLIFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEAR 67
            :|||||||||||||||||||||:||::......|||...||:.|:|.:..|..|| .:..:.|.|
 Frog     9 VEDVQKHSVHTLIFRSLKRTHDMFVADNAKPIPIDEESHKLKMSVKLRTEYSSVL-HMPVLKENR 72

  Fly    68 KA------------SGAQT-------------PGDKTLAITDGSATDAASGAGSLVKYNAGARP- 106
            :.            .|.::             ||....|.|......:.|.|.||    |.|.|
 Frog    73 EKGHHEAYEHYTAHQGTESEYMLTGTHPYPSGPGVALTADTQIQRMPSESAAQSL----ALALPP 133

  Fly   107 ------AEKTAPLVTGTHTSLVRASLAN----SNADMSANGAIASHLQLIPKKAPSIPKPKWHAP 161
                  |::||..|...:........:.    |.|.|.:.|  ..:..|:.||||::|||:||.|
 Frog   134 SQSRLEAQRTAASVGDIYRHAGHPERSQPPGLSMASMESGG--TKNSALVAKKAPTMPKPQWHPP 196

  Fly   162 WKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKH 226
            |||.||||||||||||:||||||:||.||:.||.||||||||||||||||||:||||||.||.:.
 Frog   197 WKLYRVISGHLGWVRCLAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSGRS 261

  Fly   227 PYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANV 291
            |||||||||:||||||||||||||||||||||||.|.||||||||.|..|||||||||:||||.|
 Frog   262 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKAGV 326

  Fly   292 HTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFA 356
            |||.||||.||:|..||..|||||||||:|:||||:..||:..||||||||||::||||..|.||
 Frog   327 HTLVGHTNAVATVRCQAAEPQIITGSHDTTIRLWDMVGGKTRVTLTNHKKSVRAVVLHPRQYTFA 391

  Fly   357 SASPDNIKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAP 421
            |.||||||||:.|:|.|:||:|||.:|:|.:|.||:||||||.|||||..|||||||||||..|.
 Frog   392 SGSPDNIKQWKFPDGNFIQNLSGHNAIINTLAVNSDGVLVSGADNGTMHLWDWRTGYNFQRIHAA 456

  Fly   422 VQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEESHPINWRPDLLKRRKF 482
            |||||:|||:||||..||||.|||||||||||||||:||:.|:||:||::|:|:::||::|
 Frog   457 VQPGSLDSESGIFACTFDQSESRLITAEADKTIKVYREDETATEETHPVSWKPEIIKRKRF 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	164..458	CDD:238121	228/293 (78%)
		WD40 repeat	177..212	CDD:293791	28/34 (82%)
		WD40 repeat	218..254	CDD:293791	30/35 (86%)
		WD40 repeat	259..295	CDD:293791	28/35 (80%)
		WD40 repeat	302..337	CDD:293791	21/34 (62%)
		WD40 repeat	343..378	CDD:293791	23/34 (68%)
		WD40 repeat	386..426	CDD:293791	29/39 (74%)
		WD40 repeat	433..457	CDD:293791	20/23 (87%)
plrg1	NP_001032331.1	WD40	199..493	CDD:238121	228/293 (78%)
		WD40 repeat	212..247	CDD:293791	28/34 (82%)
		WD40 repeat	253..289	CDD:293791	30/35 (86%)
		WD40 repeat	294..330	CDD:293791	28/35 (80%)
		WD40 repeat	337..372	CDD:293791	21/34 (62%)
		WD40 repeat	378..413	CDD:293791	23/34 (68%)
		WD40 repeat	419..458	CDD:293791	27/38 (71%)
		WD40 repeat	465..492	CDD:293791	22/26 (85%)