DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and alphaCOP

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_477395.1 Gene:alphaCOP / 38199 FlyBaseID:FBgn0025725 Length:1234 Species:Drosophila melanogaster


Alignment Length:269 Identity:69/269 - (25%)
Similarity:115/269 - (42%) Gaps:35/269 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   175 VRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVK 239
            |:.::..|...|........||::||.....|......|...|||||...:.|...|.|:|.::|
  Fly    12 VKGLSFHPKRPWILVSLHSGVIQLWDYRMHTLLEKFDEHDGPVRGVAFHQQMPLFVSGGDDYKIK 76

  Fly   240 CWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASV 304
            .|:.:..:.|.....||..|.::|.|.....:.::..|.|.|||:.:::..:..||||.:.|...
  Fly    77 VWNYKQRRCIFTLLAHLDYVRTVAFHHEYPWILSASDDQTIRIWNWQSRNCICVLTGHNHYVMCA 141

  Fly   305 VAQATNPQIITGSHDSTVRLWDLAA--GKSVC-----------------------------TLTN 338
            ....|..||::.|.|.|||:||::.  .|:|.                             .|..
  Fly   142 QFHPTEDQIVSASLDQTVRVWDISGLRKKNVAPGPGGLDDHLKGHPGATDLFGQADAVVKHVLEG 206

  Fly   339 HKKSVRSIVLHPSLYMFASASPDN-IKQWRCPEGKF--VQNISGHTSIVNCMAAN-SEGVLVSGG 399
            |.:.|.....||:|.:..|.:.|. :|.||..|.|.  |....||.:.|:.:..: .:.:::|.|
  Fly   207 HDRGVNWASFHPTLPLIVSGADDRLVKLWRMNEYKAWEVDTCRGHYNNVSSVLFHPRQDLILSNG 271

  Fly   400 DNGTMFFWD 408
            ::.::..||
  Fly   272 EDRSIRVWD 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 69/269 (26%)
WD40 164..458 CDD:238121 69/269 (26%)
WD40 repeat 177..212 CDD:293791 7/34 (21%)
WD40 repeat 218..254 CDD:293791 11/35 (31%)
WD40 repeat 259..295 CDD:293791 8/35 (23%)
WD40 repeat 302..337 CDD:293791 12/65 (18%)
WD40 repeat 343..378 CDD:293791 12/37 (32%)
WD40 repeat 386..426 CDD:293791 4/24 (17%)
WD40 repeat 433..457 CDD:293791
alphaCOPNP_477395.1 WD40 <2..320 CDD:225201 69/269 (26%)
WD40 5..321 CDD:238121 69/269 (26%)
WD40 repeat 15..49 CDD:293791 7/33 (21%)
WD40 repeat 57..91 CDD:293791 9/33 (27%)
WD40 repeat 97..133 CDD:293791 8/35 (23%)
WD40 repeat 138..205 CDD:293791 13/66 (20%)
WD40 repeat 212..249 CDD:293791 11/36 (31%)
WD40 repeat 255..291 CDD:293791 5/26 (19%)
WD40 repeat 299..352 CDD:293791
Coatomer_WDAD 354..765 CDD:281977
COPI_C 815..1228 CDD:284395
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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