DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and taf5

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_587902.1 Gene:taf5 / 2539353 PomBaseID:SPCC5E4.03c Length:643 Species:Schizosaccharomyces pombe


Alignment Length:445 Identity:111/445 - (24%)
Similarity:172/445 - (38%) Gaps:77/445 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 HDLF--VSNQGN--LPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASG------------ 71
            |.||  |||.|:  :..|::.::     |....|...||:....|.|....:|            
pombe   162 HFLFENVSNGGSIIIKLINQHID-----IHIVPGRPTVLENAKVINEQEGITGQSFERGDAQLQP 221

  Fly    72 ---AQTPGDKTL-AITDGS--------ATDAASGAGSLVKY-------NAGARPAEKTAPLVTGT 117
               .|.|.||.: .|.:..        ..|..:.:..|:|.       ||...|:....||  ..
pombe   222 VKLQQMPMDKEMEKIVEMDLEEEDMMHQNDPNNQSPKLLKEFRKLHEPNAEDAPSRDYIPL--PP 284

  Fly   118 HTSLVRASLANSNADMSANGAIASHLQLIPKKA-PSIPKPKWHAPWKLSRVISGHL-GWVRCIAV 180
            |..:...|...:..|.|      ..|.|.|:.: ||:....:|           |. ..:.|...
pombe   285 HKGVDILSEVEAVKDWS------KRLHLGPRASLPSVCMYTFH-----------HTNNNMNCAEF 332

  Fly   181 EPGNEWFATGAGDRVIKIWDLASGKLKL-------------SLTGHVSTVRGVAVSTKHPYLFSC 232
            .|.:...|.|..:..|::|.:.:.|..|             .|..|...|.|...|..:.||.||
pombe   333 SPDSTMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRLLSHSGPVYGTTFSPDNKYLLSC 397

  Fly   233 GEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGH 297
            .||...:.|.::....:..|.||...|:.:|..|.....||:..|.||::|.......:....||
pombe   398 SEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWSCDHIYPLRVFAGH 462

  Fly   298 TNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDN 362
            .:.|..|.....:..::|||.|.|.||||:..|.||.....|.:.|.::.:.|..:..|||..:.
pombe   463 LSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEG 527

  Fly   363 -IKQWRCPEGKFVQNISGHTSIVNCMAANSEG-VLVSGGDNGTMFFWD-WRTGYN 414
             |..|....|:.::.:.||...:..::.:.|. ||||||.:.|:..|| ::|.||
pombe   528 LIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFKTNYN 582

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 73/271 (27%)
WD40 164..458 CDD:238121 73/268 (27%)
WD40 repeat 177..212 CDD:293791 9/47 (19%)
WD40 repeat 218..254 CDD:293791 10/35 (29%)
WD40 repeat 259..295 CDD:293791 9/35 (26%)
WD40 repeat 302..337 CDD:293791 13/34 (38%)
WD40 repeat 343..378 CDD:293791 8/35 (23%)
WD40 repeat 386..426 CDD:293791 13/31 (42%)
WD40 repeat 433..457 CDD:293791
taf5NP_587902.1 LisH 10..36 CDD:285685
TFIID_NTD2 54..177 CDD:282363 7/14 (50%)
WD40 <316..588 CDD:225201 74/278 (27%)
WD40 repeat 329..377 CDD:293791 9/47 (19%)
WD40 <332..575 CDD:238121 66/242 (27%)
WD40 repeat 383..419 CDD:293791 10/35 (29%)
WD40 repeat 424..460 CDD:293791 9/35 (26%)
WD40 repeat 467..502 CDD:293791 13/34 (38%)
WD40 repeat 508..544 CDD:293791 8/35 (23%)
WD40 repeat 550..590 CDD:293791 13/33 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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