DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and Y32H12A.8

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_498151.2 Gene:Y32H12A.8 / 175742 WormBaseID:WBGene00021316 Length:3849 Species:Caenorhabditis elegans


Alignment Length:282 Identity:64/282 - (22%)
Similarity:100/282 - (35%) Gaps:59/282 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 VISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDL---ASGKLKLSLTGHVSTVRGVAVSTK--- 225
            |:||..|.::.|.::  |.......|..::|..|:   ..||:.:..:         |.:.|   
 Worm    59 VVSGIRGVLQIIKIQ--NSTNDLIEGPSIVKDLDMRVYRKGKVNILYS---------AQNVKWNQ 112

  Fly   226 --HPYLFSCGEDRQVKCWDL-EYNKVIRHYHGHLSAVYSLALHPTIDVLATSG-RDSTARIWDMR 286
              ..|:.:...:..:.||:: ..||.:  :..|..:...|..|.|...:..|| ||.|.:.:|||
 Worm   113 LYDQYIATTSSNGSIVCWNISRRNKSV--FKSHERSATCLDWHATTPYILVSGSRDCTVKSYDMR 175

  Fly   287 TKANVHTLTGHTNTVASV--VAQATNP----QIITGSHDSTVRLWDLAAGKS-VCTLTNHKKSVR 344
            .|.| |.||.......|:  ||....|    ...||.....:|||||...:. |.....|:..|.
 Worm   176 VKDN-HQLTFSDRNCESIRDVAMCKAPGFDDYFFTGDDGGVLRLWDLRQTRRWVFQKVAHRSFVS 239

  Fly   345 SIVLHP---SLYMFASASPDNIKQWR---------------CPEGKFVQNISGHTSIVNCMAANS 391
            ::.|:|   :|..........:|.|.               .|.|:..........:..|.:.|.
 Worm   240 TLSLNPHNRTLIATGGGRDKMVKIWEWTGPELNRISVVETTAPLGRVAWRPDRPYHLATCASVNE 304

  Fly   392 EGVLVSGGDNGTMFFWDWRTGY 413
            ..|.|          ||.|..|
 Worm   305 TSVHV----------WDVRRPY 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 64/282 (23%)
WD40 164..458 CDD:238121 64/282 (23%)
WD40 repeat 177..212 CDD:293791 7/37 (19%)
WD40 repeat 218..254 CDD:293791 7/41 (17%)
WD40 repeat 259..295 CDD:293791 14/36 (39%)
WD40 repeat 302..337 CDD:293791 12/41 (29%)
WD40 repeat 343..378 CDD:293791 8/52 (15%)
WD40 repeat 386..426 CDD:293791 8/28 (29%)
WD40 repeat 433..457 CDD:293791
Y32H12A.8NP_498151.2 WD40 repeat 106..142 CDD:293791 6/37 (16%)
WD40 136..>360 CDD:392136 48/194 (25%)
WD40 repeat 148..197 CDD:293791 18/49 (37%)
WD40 repeat 202..230 CDD:293791 8/27 (30%)
WD40 repeat 239..267 CDD:293791 5/27 (19%)
WD40 repeat 274..323 CDD:293791 10/53 (19%)
WD40 repeat 329..372 CDD:293791
mRING-H2-C3H3C2_Mio 787..835 CDD:319605
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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