DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and mec-15

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_496207.1 Gene:mec-15 / 174587 WormBaseID:WBGene00003177 Length:406 Species:Caenorhabditis elegans


Alignment Length:268 Identity:58/268 - (21%)
Similarity:102/268 - (38%) Gaps:50/268 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   161 PWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTK 225
            ||.:::..:.|.||:..:|.|..:..|.|.:.|..:|.|.:..       .|.:..:..|.|.:.
 Worm   147 PWTVAKDDTAHSGWIWNMAQESTSTNFYTTSWDSTVKSWHITD-------NGALQNLNSVNVGSA 204

  Fly   226 HPYLFSCGEDRQVKCW---------DLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTAR 281
            ...:...|.:.:|.|.         |....:|:..:..|..||.:||:..  |.:.|||.|....
 Worm   205 AQCISCSGNENEVVCTTFAKRVAVIDSRTFQVVADHKLHKRAVIALAVQG--DKIFTSGEDRLMM 267

  Fly   282 IWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWD-----LAAGKSVCTLTN--- 338
            :.|.|..:.............|.::...| |::|.:.|..|:|:|     :....||.:.|.   
 Worm   268 MVDRRNFSKPVLFEYSPTAYKSCLSLQCN-QLLTSTSDGKVKLYDANNFNVLQTYSVGSYTRQSF 331

  Fly   339 -----HKKSVRSIVLHPSLYMFASASPDNIKQWRC---------------PEGKFVQNISGHTSI 383
                 |....||:..:   |.|:..||....|..|               |..:.:...:|.:||
 Worm   332 LEHGAHLIMARSLKRN---YTFSIYSPGTRSQQWCASHELAAEPAKFDYSPSSRTLAIGNGDSSI 393

  Fly   384 VNCMAANS 391
            :.|:.|::
 Worm   394 LFCLPASA 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 58/268 (22%)
WD40 164..458 CDD:238121 56/265 (21%)
WD40 repeat 177..212 CDD:293791 7/34 (21%)
WD40 repeat 218..254 CDD:293791 7/44 (16%)
WD40 repeat 259..295 CDD:293791 10/35 (29%)
WD40 repeat 302..337 CDD:293791 10/39 (26%)
WD40 repeat 343..378 CDD:293791 9/49 (18%)
WD40 repeat 386..426 CDD:293791 2/6 (33%)
WD40 repeat 433..457 CDD:293791
mec-15NP_496207.1 F-box-like 9..52 CDD:315592
WD40 88..322 CDD:330360 40/184 (22%)
WD40 repeat 106..154 CDD:293791 2/6 (33%)
WD40 repeat 162..197 CDD:293791 8/41 (20%)
WD40 repeat 204..241 CDD:293791 5/36 (14%)
WD40 repeat 247..286 CDD:293791 10/40 (25%)
WD40 repeat 290..310 CDD:293791 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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