DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and F55F8.3

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_491653.2 Gene:F55F8.3 / 172224 WormBaseID:WBGene00018891 Length:910 Species:Caenorhabditis elegans


Alignment Length:298 Identity:62/298 - (20%)
Similarity:111/298 - (37%) Gaps:61/298 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   188 ATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYL-FSCGE--DRQVKCWDLEYNKVI 249
            ||...:.||.:.::.|..|..:|......::.||.:....:| ..||:  ..|:..|:.:....:
 Worm   289 ATAFNNGVIVLHEIPSFALVHNLRVSEMRIQTVAWNLTGDWLAIGCGKGSTAQLVVWEWQSESYV 353

  Fly   250 RHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQII 314
            .....|...:.:....|...::||...|...:||:.|:.....|...||:.|.:|....:...|:
 Worm   354 MKQQAHSLRITTAEYSPDGSLMATGAEDGKVKIWNSRSSFCTVTFDEHTSGVTAVKWTQSGRAIL 418

  Fly   315 TGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISG 379
            :.|.|.|||..||...::..||.                              |||         
 Worm   419 SASLDGTVRAHDLKRYRNFRTLV------------------------------CPE--------- 444

  Fly   380 HTSIVNCMAANSEGVLVSGG--DNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSG 442
            .|.:.. :|.:..|.||..|  :...::.|.:.||:.......        .|:.|.::  |..|
 Worm   445 PTQLAT-LAVDKAGDLVIAGAKEVFNIYIWSFETGHLLDILSG--------HESAISSI--DIHG 498

  Fly   443 SRLITAEADKTIKVY------KEDDEASEESHPINWRP 474
            :.:::...|:|||::      .|..|.|.|:..:.:.|
 Worm   499 NHIVSGSWDRTIKMWTIVDSQAETVEVSHEALDVKFSP 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 57/280 (20%)
WD40 164..458 CDD:238121 57/280 (20%)
WD40 repeat 177..212 CDD:293791 7/23 (30%)
WD40 repeat 218..254 CDD:293791 7/38 (18%)
WD40 repeat 259..295 CDD:293791 8/35 (23%)
WD40 repeat 302..337 CDD:293791 10/34 (29%)
WD40 repeat 343..378 CDD:293791 3/34 (9%)
WD40 repeat 386..426 CDD:293791 8/41 (20%)
WD40 repeat 433..457 CDD:293791 7/23 (30%)
F55F8.3NP_491653.2 WD40 58..427 CDD:225201 31/137 (23%)
WD40 repeat 58..94 CDD:293791
WD40 96..427 CDD:295369 31/137 (23%)
WD40 repeat 99..144 CDD:293791
WD40 repeat 150..188 CDD:293791
WD40 repeat 193..256 CDD:293791
WD40 248..618 CDD:225201 62/298 (21%)
WD40 repeat 277..312 CDD:293791 6/22 (27%)
WD40 repeat 318..358 CDD:293791 7/39 (18%)
WD40 321..608 CDD:295369 55/266 (21%)
WD40 repeat 364..400 CDD:293791 8/35 (23%)
WD40 repeat 405..441 CDD:293791 11/35 (31%)
WD40 repeat 449..485 CDD:293791 8/36 (22%)
WD40 repeat 491..524 CDD:293791 8/34 (24%)
WD40 repeat 530..584 CDD:293791 1/7 (14%)
WD40 repeat 591..613 CDD:293791
WD40 repeat 661..692 CDD:293791
Utp12 760..861 CDD:281932
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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