Protein Alignment Tango4 and AAMP

DIOPT Version :9

• Sequence 1: NP_572778.1
• Gene: Tango4 / 32168
• FlyBaseID: FBgn0030365
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: XP_024308480.1
• Gene: AAMP / 14
• HGNCID: 18
• Length: 459
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 59/306 - (19%)
• Similarity: 100/306 - (32%)
• Gaps: 96/306 - (31%)

  Fly   171 HLGWVRCIAVEPGNEWFA-TGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGE 234
            |...|.|::::|.....| ||..|....:|.|:.|:|.....||..:|.....|.....:.:...
Human    90 HSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDM 154

  Fly   235 DRQVKCWDLEYNKVIRHYH-GHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHT 298
            ...:|.|.::..:.:..:. |.|.   .:..||...||.....|....:|.:.        .|..
Human   155 SGLLKVWQVDTKEEVWSFEAGDLE---WMEWHPRAPVLLAGTADGNTWMWKVP--------NGDC 208

  Fly   299 NTVASVVAQAT-------NPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFA 356
            .|.......||       ..:.:.|..|.|:|:|||..|
Human   209 KTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQG-------------------------- 247

  Fly   357 SASPDNIKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAP 421
              ||.::          ::...||...:.|:|||.:|.|
Human   248 --SPIHV----------LKGTEGHQGPLTCVAANQDGSL-------------------------- 274

  Fly   422 VQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEES 467
            :..||:|.:|            :|::|...|.:.|::.:..||:.|
Human   275 ILTGSVDCQA------------KLVSATTGKVVGVFRPETVASQPS 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	56/295 (19%)
		WD40	164..458	CDD:238121	56/295 (19%)
		WD40 repeat	177..212	CDD:293791	10/35 (29%)
		WD40 repeat	218..254	CDD:293791	3/36 (8%)
		WD40 repeat	259..295	CDD:293791	6/35 (17%)
		WD40 repeat	302..337	CDD:293791	10/41 (24%)
		WD40 repeat	343..378	CDD:293791	2/34 (6%)
		WD40 repeat	386..426	CDD:293791	6/39 (15%)
		WD40 repeat	433..457	CDD:293791	3/23 (13%)
AAMP	XP_024308480.1	WD40	86..361	CDD:238121	59/306 (19%)
		WD40 repeat	94..132	CDD:293791	11/37 (30%)
		WD40 repeat	169..212	CDD:293791	10/53 (19%)
		WD40 repeat	219..254	CDD:293791	11/72 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53955
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920