Protein Alignment Tango4 and Tango4

DIOPT Version :10

• Sequence 1: NP_572778.1
• Gene: Tango4 / 32168
• FlyBaseID: FBgn0030365
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: XP_315646.4
• Gene: Tango4 / 1276316
• VectorBaseID: AGAMI1_010547
• Length: 461
• Species: Anopheles gambiae
• Alignment Length: 492
• Identity: 366/492 - (74%)
• Similarity: 404/492 - (82%)
• Gaps: 43/492 - (8%)

  Fly     3 MEDVQKHSVHTLIFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLDKVAKI---- 63
            ||:||:||||||:|||||||||.||:||..||||||.||||:.:|||:|.||||.|:.||.
Mosquito     1 MEEVQRHSVHTLVFRSLKRTHDFFVANQSLLPEIDETLEKLKYNIKARDTYGLVFDRAAKAKALA 65

  Fly    64 ---GEARKASGAQTPGDKTLAIT-----DGSATDAASGAGSLVKYNAGARPAEKTAPLVTGTHTS 120
               |::.:..|.....|..||||     :|||.|..:|..:||       ||....|
Mosquito    66 AKRGDSDRIEGQHGGKDGVLAITAAGEQEGSAPDGTNGQMALV-------PASTPTP-------- 115

  Fly   121 LVRASLANSNADMSANGAIASHLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEPGNE 185
                 .|.|||           :|::|||||:||||||||||||.||||||||||||:|||||||
Mosquito   116 -----QAASNA-----------VQILPKKAPTIPKPKWHAPWKLCRVISGHLGWVRCVAVEPGNE 164

  Fly   186 WFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIR 250
            ||||||.||||||||||||||||||||||||||.:|||.:|||||||||||||||||||||||||
Mosquito   165 WFATGAADRVIKIWDLASGKLKLSLTGHVSTVRALAVSPRHPYLFSCGEDRQVKCWDLEYNKVIR 229

  Fly   251 HYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIIT 315
            ||||||||||:::||||||||.|:|||||||:||||||||:||||||||||||||.||.||||||
Mosquito   230 HYHGHLSAVYTMSLHPTIDVLVTAGRDSTARVWDMRTKANIHTLTGHTNTVASVVTQAANPQIIT 294

  Fly   316 GSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISGH 380
            |||||||||||||||||:|||||||||||:||||||||||||||||||||||||||.|:||:.||
Mosquito   295 GSHDSTVRLWDLAAGKSMCTLTNHKKSVRAIVLHPSLYMFASASPDNIKQWRCPEGNFIQNLGGH 359

  Fly   381 TSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRL 445
            .|||||||.|.|||||||||||||||||||||||||||||.|||||||||||||:|.||||||||
Mosquito   360 NSIVNCMAVNPEGVLVSGGDNGTMFFWDWRTGYNFQRFQAAVQPGSMDSEAGIFSMTFDQSGSRL 424

  Fly   446 ITAEADKTIKVYKEDDEASEESHPINWRPDLLKRRKF 482
            ||.|||||||:|||||||:||||||||||:::||||:
Mosquito   425 ITTEADKTIKIYKEDDEATEESHPINWRPEIIKRRKY 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	164..458	CDD:238121	263/293 (90%)
		WD40 repeat	177..212	CDD:293791	32/34 (94%)
		WD40 repeat	218..254	CDD:293791	31/35 (89%)
		WD40 repeat	259..295	CDD:293791	28/35 (80%)
		WD40 repeat	302..337	CDD:293791	31/34 (91%)
		WD40 repeat	343..378	CDD:293791	31/34 (91%)
		WD40 repeat	386..426	CDD:293791	36/39 (92%)
		WD40 repeat	433..457	CDD:293791	20/23 (87%)
Tango4	XP_315646.4	None