DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango4 and AgaP_AGAP005429

DIOPT Version :9

Sequence 1:	NP_572778.1	Gene:	Tango4 / 32168	FlyBaseID:	FBgn0030365	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	XP_315435.4	Gene:	AgaP_AGAP005429 / 1276126	VectorBaseID:	AGAP005429	Length:	334	Species:	Anopheles gambiae

Alignment Length:	178	Identity:	45/178 - (25%)
Similarity:	77/178 - (43%)	Gaps:	30/178 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 SANGAIASHLQLIPKKAPSIPK---------PKWHAPWKLSRVISGHLGWVRCIAVEPGNEWFAT 189
            |.|.|.:..|:|  .:.|::|.         |.:...:....:|.|..|.: |     |.:| ::
Mosquito    43 SCNAADSPPLEL--DQLPTVPLQTLSVTDRCPIYSLSFHKDFLIVGLNGEI-C-----GFQW-SS 98

  Fly   190 GAGDRVIKIWDLASGKLKLSL---TGHVSTVRGVAVSTKHPYLFS-CGEDRQVKCWDLEYNKVIR 250
            .||....|.|     .:||..   :..:|.|..:.::.|...|:: || |..:....||..||.|
Mosquito    99 KAGTIGKKAW-----TVKLPAPPESADMSEVNYMWLNAKDDMLYAGCG-DNVLYGVSLEDGKVCR 157

  Fly   251 HYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHT 298
            .:|||...::.::  ..:..|||:..|.:..:||.|.|.:...:..||
Mosquito   158 EFHGHTDYIHCVS--GCVGKLATASEDGSVLLWDSRQKTSYAKIEPHT 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	37/142 (26%)
		WD40	164..458	CDD:238121	37/139 (27%)
		WD40 repeat	177..212	CDD:293791	9/37 (24%)
		WD40 repeat	218..254	CDD:293791	10/36 (28%)
		WD40 repeat	259..295	CDD:293791	8/35 (23%)
		WD40 repeat	302..337	CDD:293791
		WD40 repeat	343..378	CDD:293791
		WD40 repeat	386..426	CDD:293791
		WD40 repeat	433..457	CDD:293791
AgaP_AGAP005429	XP_315435.4	WD40	11..>315	CDD:225201	45/178 (25%)
		WD40 repeat	13..67	CDD:293791	7/25 (28%)
		WD40	<18..248	CDD:295369	45/178 (25%)
		WD40 repeat	73..117	CDD:293791	12/55 (22%)
		WD40 repeat	125..160	CDD:293791	10/35 (29%)
		WD40 repeat	166..208	CDD:293791	10/40 (25%)
		WD40 repeat	216..253	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910