DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango4 and LOC100490380

DIOPT Version :9

Sequence 1:	NP_572778.1	Gene:	Tango4 / 32168	FlyBaseID:	FBgn0030365	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	XP_004912816.1	Gene:	LOC100490380 / 100490380	-ID:	-	Length:	399	Species:	Xenopus tropicalis

Alignment Length:	228	Identity:	49/228 - (21%)
Similarity:	81/228 - (35%)	Gaps:	66/228 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 SAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDST 321
            :||.::|.||:.|:||....|....::                                     :
Frog    48 AAVNTIAFHPSQDILAAGDVDGDVFVY-------------------------------------S 75

  Fly   322 VRLWDLAAGKSVCTLTNHKKSVR-SIVLHPSLYMFASASPDNIKQWRCPEGKFVQNI-SGHTSIV 384
            ...|: :..|.:.:..:|.||.| |........:|..:....|......|||.::.| ..|.|.:
Frog    76 YSCWE-SGNKELWSSGHHLKSCRDSAFTSDGQQLFTVSKDKAIHILSMEEGKLIKRIPKAHDSPL 139

  Fly   385 NCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAE 449
            ||:....|.:..:|.|||.:..||.|...:|...:        :.|..|..|..|::...|:||.
Frog   140 NCLLLIDENLFATGDDNGMLKVWDLRRDTSFMEMK--------NHEEYISDMAIDENKKMLLTAS 196

  Fly   450 ADKTIKVYKEDDEASEESHPINWRPDLLKRRKF 482
            .|.|:.|:.                  :|||:|
Frog   197 GDGTMGVFN------------------IKRRRF 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	45/202 (22%)
		WD40	164..458	CDD:238121	45/202 (22%)
		WD40 repeat	177..212	CDD:293791
		WD40 repeat	218..254	CDD:293791
		WD40 repeat	259..295	CDD:293791	8/35 (23%)
		WD40 repeat	302..337	CDD:293791	2/34 (6%)
		WD40 repeat	343..378	CDD:293791	8/36 (22%)
		WD40 repeat	386..426	CDD:293791	10/39 (26%)
		WD40 repeat	433..457	CDD:293791	8/23 (35%)
LOC100490380	XP_004912816.1	WD40	47..332	CDD:392136	49/228 (21%)
		WD40 repeat	51..88	CDD:293791	9/74 (12%)
		WD40 repeat	98..133	CDD:293791	7/34 (21%)
		WD40 repeat	139..175	CDD:293791	11/43 (26%)
		WD40 repeat	180..215	CDD:293791	13/50 (26%)
		WD40 repeat	223..264	CDD:293791
		WD40 repeat	271..299	CDD:293791
		WD40 repeat	307..333	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910